Actin machinery: pushing the envelope

被引：385
作者：
Borisy, GG [1 ]
Svitkina, TM [1 ]
机构：
[1] Univ Wisconsin, Mol Biol Lab, Madison, WI 53706 USA
来源：
CURRENT OPINION IN CELL BIOLOGY | 2000年 / 12卷 / 01期
关键词：
D O I：
10.1016/S0955-0674(99)00063-0
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The reconstitution of microbial rocketing motility in vitro with purified proteins has recently established definitively that no myosin motor is required for protrusion. Instead, actin polymerization, in conjunction with a small number of proteins, is sufficient. A dendritic pattern of nucleation controlled by the Arp2/3 complex provides an efficient pushing force for lamellipodial motility.
引用
收藏
页码：104 / 112
页数：9
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