Hormesis is an appealing concept when considered from the evolutionary viewpoint. It may provide a new approach to deriving the 'no observed adverse effect level' for occupational exposures to chemicals. An over-reliance on mathematical modeling without a clear understanding of exposures and health outcomes stymies current scientific decision-making. Care must be taken, however, as not all endpoints will exhibit a hormetic response.
机构:
SUNY, Sch Publ Hlth, New York State Dept Transportat, Manlius, NY 13104 USASUNY, Sch Publ Hlth, New York State Dept Transportat, Manlius, NY 13104 USA