Calcium signals control wnt-dependent dendrite growth

被引：9

作者：

Alvania, Rebecca S. ^{[1
]}

Chen, Xi ^{[1
]}

Ginty, David D. ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Howard Hughes Med Inst, Dept Neurosci, Baltimore, MD 21205 USA

来源：

NEURON | 2006年 / 50卷 / 06期

关键词：

D O I：

10.1016/j.neuron.2006.06.001

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Activity-dependent dendritic growth is dependent upon intracellular calcium signaling. Yet the specific mechanisms by which calcium signals lead to morphologic changes in dendrites are not well understood. A paper in this issue of Neuron by Wayman et al. describes a novel calcium-dependent signaling cascade linking neuronal activity and calcium influx to expression of Wnt-2, a member of a family of proteins that controls elaboration of dendrites.

引用

页码：813 / 815

页数：3

共 11 条

[1] WNTs in the vertebrate nervous system: From patterning to neuronal connectivity [J].

Ciani, L ;

Salinas, PC .

NATURE REVIEWS NEUROSCIENCE, 2005, 6 (05) :351-U17

[2] Defining the CREB regulon: A genome-wide analysis of transcription factor regulatory regions [J].

Impey, S ;

McCorkle, SR ;

Cha-Molstad, H ;

Dwyer, JM ;

Yochum, GS ;

Boss, JM ;

McWeeney, S ;

Dunn, JJ ;

Mandel, G ;

Goodman, RH .

CELL, 2004, 119 (07) :1041-1054

[3] Transmitter-evoked local calcium release stabilizes developing dendrites [J].

Lohmann, C ;

Myhr, KL ;

Wong, ROL .

NATURE, 2002, 418 (6894) :177-181

[4] Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription [J].

Redmond, L ;

Kashani, AH ;

Ghosh, A .

NEURON, 2002, 34 (06) :999-1010

[5] Cerebellar defects in Ca2+/calmodulin kinase IV-deficient mice [J].

Ribar, TJ ;

Rodriguiz, RM ;

Khiroug, L ;

Wetsel, WC ;

Augustine, GJ ;

Means, AR .

JOURNAL OF NEUROSCIENCE, 2000, 20 (22)

[6] Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development [J].

Rosso, SB ;

Sussman, D ;

Wynshaw-Boris, A ;

Salinas, PC .

NATURE NEUROSCIENCE, 2005, 8 (01) :34-42

[7] Calcium activation of ERK mediated by calmodulin kinase I [J].

Schmitt, JM ;

Wayman, GA ;

Nozaki, N ;

Soderling, TR .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (23) :24064-24072

[8] Identification of a signaling pathway involved in calcium regulation of BDNF expression [J].

Shieh, PB ;

Hu, SC ;

Bobb, K ;

Timmusk, T ;

Ghosh, A .

NEURON, 1998, 20 (04) :727-740

[9] Regulation of axonal extension and growth cone motility by calmodulin-dependent protein kinase I [J].

Wayman, GA ;

Kaech, S ;

Grant, WF ;

Davare, M ;

Impey, S ;

Tokumitsu, H ;

Nozaki, N ;

Banker, G ;

Soderling, TR .

JOURNAL OF NEUROSCIENCE, 2004, 24 (15) :3786-3794

[10] Activity-dependent dendritic arborization mediated by CaM-Kinase I activation and enhanced CREB-dependent transcription of Wnt-2 [J].

Wayman, Gary A. ;

Impey, Soren ;

Marks, Daniel ;

Saneyoshi, Takeo ;

Grant, Wilmon F. ;

Derkach, Victor ;

Soderling, Thomas R. .

NEURON, 2006, 50 (06) :897-909

← 1 2 →