Harnessing G-tetrad scaffolds within G-quadruplex forming aptamers for fluorescence detection strategies

被引：20

作者：

Sproviero, Michael ^{[1
]}

Manderville, Richard A. ^{[1
]}

机构：

[1] Univ Guelph, Dept Chem & Toxicol, Guelph, ON N1G 2W1, Canada

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 23期

关键词：

THROMBIN-BINDING APTAMER; DNA; OLIGONUCLEOTIDE; STABILITY; PROBES;

D O I：

10.1039/c3cc49560d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

G-tetrads are essential structural components required for the formation of G-quadruplexes. Replacement of G nucleobases within G-tetrads with fluorescent 8-aryl-dG residues provides diagnostic handles that are universally applicable to antiparallel G-quadruplex aptamers, as they can stabilize quadruplex folding and maintain aptamer function.

引用

页码：3097 / 3099

页数：3

共 50 条

[21] Fluorescence Detection of Potassium Ion Using the G-Quadruplex Structure
Takenaka, Shigeori
Juskowiak, Bernard
ANALYTICAL SCIENCES, 2011, 27 (12) : 1167 - 1172
[22] Fluorescence detection of the human angiotensinogen protein by the G-quadruplex aptamer
Xi, Hui
Jiang, Hanlin
Juhas, Mario
Zhang, Yang
ANALYST, 2022, 147 (18) : 4040 - 4048
[23] Fluorescence detection of adenosine triphosphate based on dimeric G-quadruplex
Xiao, Qiangsheng
Chen, Yangfan
Yu, Xiao
Nie, Wanpin
Liu, Birong
Ma, Changbei
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2025, 326
[24] Multicarbazole scaffolds for selective G-quadruplex binding
Ou, Arnold
Guedin, Aurore
Skelton, Brian W.
Amrane, Samir
Evans, Cameron W.
Norret, Marck
Iyer, K. Swaminathan
Mergny, Jean-Louis
Smith, Nicole M.
CHEMICAL COMMUNICATIONS, 2018, 54 (69) : 9647 - 9650
[25] Fluorescence detection of glyphosate based on G-quadruplex and porphyrin metalation
Fang, Huajuan
Zhang, Xingping
Ma, Liyuan
Xiao, Yao
Yang, Hualin
Zhou, Yu
JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 2023, 116
[26] Fluorescence method for kanamycin detection based on the conversion of G-triplex and G-quadruplex
Wang, Chengke
Li, Jiangyu
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 413 (28) : 7073 - 7080
[27] Fluorescence method for kanamycin detection based on the conversion of G-triplex and G-quadruplex
Chengke Wang
Jiangyu Li
Analytical and Bioanalytical Chemistry, 2021, 413 : 7073 - 7080
[28] G-Quadruplex Forming Sequence Modulated Transcription
Lee, Chun-Ying
McNerney, Christina
Ma, Kevin
Myong, Sua
BIOPHYSICAL JOURNAL, 2019, 116 (03) : 209A - 209A
[29] Potential uses of G-quadruplex-forming aptamers
Viglasky, Viktor
Hianik, Tibor
GENERAL PHYSIOLOGY AND BIOPHYSICS, 2013, 32 (02) : 149 - 172
[30] G-quadruplex DNA Aptamers and their Ligands: Structure, Function and Application
Tucker, W. O.
Shum, K. T.
Tanner, J. A.
CURRENT PHARMACEUTICAL DESIGN, 2012, 18 (14) : 2014 - 2026

← 1 2 3 4 5 →