Ocular Manifestations of Scleroderma

被引：66

作者：

Tailor, Rajen ^{[1
]}

Gupta, Abha ^{[2
]}

Herrick, Ariane ^{[3
]}

Kwartz, Jeffrey ^{[4
]}

机构：

[1] City Hosp, Birmingham & Midlands Eye Ctr, Birmingham B18 7QH, W Midlands, England

[2] Calderdale Royal Hosp, Halifax, NS, Canada

[3] Univ Manchester, Ctr Rheumat Dis, Salford, Lancs, England

[4] Royal Bolton Hosp, Eye Unit, Bolton, England

来源：

SURVEY OF OPHTHALMOLOGY | 2009年 / 54卷 / 02期

关键词：

pathogenesis; scleroderma; systemic sclerosis; ENDOTHELIAL-CELL APOPTOSIS; RETINAL VEIN OCCLUSION; SYSTEMIC-SCLEROSIS; GLAUCOMATOUS ABNORMALITIES; FLUORESCEIN ANGIOGRAPHY; HUMAN CYTOMEGALOVIRUS; FIBROGENIC CYTOKINES; SERUM AUTOANTIBODIES; INCREASED PREVALENCE; GENE-EXPRESSION;

D O I：

10.1016/j.survophthal.2008.12.007

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Systemic sclerosis is a chronic multi-system disorder predominantly affecting the skin, musculoskeletal, gastrointestinal, pulmonary, and renal systems. Although the exact etiology is unknown, recent evidence suggests that immune activation play a pivotal role in the pathogenesis. Ocular involvement in systemic sclerosis has been documented; however, due to the rare nature of the disease, most papers have been single case reports or small case series. This review paper aims to consolidate the findings of previous papers with a view to providing a comprehensive review of the ocular manifestations of systemic sclerosis. (Surv Ophthalmol 54:292-304,2009. (C) 2009 Elsevier Inc. All rights reserved.)

引用

页码：292 / 304

页数：13

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