Seroprevalence and risk factors on Syphilis among blood donors in Chengdu, China,from 2005 to 2017

被引:18
作者
Liu, Shuangli [1 ]
Luo, Liping [2 ]
Xi, Guangxiang [3 ]
Wan, Like [4 ]
Zhong, Li [5 ]
Chen, Xue [6 ]
Gong, Tianxiang [7 ]
Li, Shuping [7 ]
He, Yi [7 ,8 ]
Li, Na [7 ]
机构
[1] Chengdu Blood Ctr, Dept Blood Collect, Chengdu, Sichuan, Peoples R China
[2] Yibin Blood Stn, Yibin, Peoples R China
[3] Chengdu Blood Ctr, Dept Blood Supply, Chengdu, Sichuan, Peoples R China
[4] Chengdu Blood Ctr, Dept Blood Preparat, Chengdu, Sichuan, Peoples R China
[5] Chengdu Blood Ctr, Dept Donor Serv, Chengdu, Sichuan, Peoples R China
[6] Chengdu Blood Ctr, Blood Screening Lab, Chengdu, Sichuan, Peoples R China
[7] Chengdu Blood Ctr, Blood Res Lab, Chengdu, Sichuan, Peoples R China
[8] Chengdu Blood Ctr, Dept Qual Control, Chengdu, Sichuan, Peoples R China
关键词
Syphilis; Risk factors; Blood safety; Health consultation; Blood donors; HIV; DONATION; COLLEGE; HBV; HCV; PREVALENCE; STUDENTS; MEN; SEX;
D O I
10.1186/s12879-019-4128-7
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
BackgroundHigh-risk population of blood donation increases the prevalence of transmit blood-borne diseases and harm the blood safety. Syphilis accounts for approximately 10% of commonly sexually transmitted diseases. The risk factors for blood donors infected with syphilis are also risk factors for other blood borne diseases. The objective of the study is to investigate the seroprevalence and risk factors on syphilis among blood donors, and analyze the donation status of high-risk population.MethodsA retrospective study was conducted in Chengdu Blood Center during 2005 and 2017. Serological test results of volunteer blood donors were collected. Conditional logistic regression models were performed to investigate syphilis-related risk factors and population attributable risk (PAR) was performed to predict the tendencies of high-risk populations' on risky behaviors.ResultsThe serological epidemic for syphilis among blood donors in Chengdu showed an upward trend from 2005 to 2017.TP positive blood donors were more likely to have multiple sexual partners and commercial sex (50.6% vs.22.6, 11.1% vs.4.6%). Multiple condition logistic regression model denoted the following risk factors for increasing rates of syphilis infections: multiple sexual partners (OR=7.1, 95% CI:1.72-6.58), razor reuse (OR=1.7;, 95% CI:1.01-2.01); ear piercing (OR=2.7, 95% CI:1.48-3.37); tattoo (OR=3.3, 95% CI:1.17-6.78); condom occasionally (OR=2.8, 95% CI:0.68-1.66). The PAR for each of the risk factors were 0.225, 0.144, 0.147, 0.018, 0.129, 0.018, respectively.ConclusionHealth consultation and screening of high-risk groups before blood donation need to be further improved. Blood donor recruitment should emphasize on excluding the high-risk donors and recruiting more low-risk blood donors. In addition, this study also shows that sharing cosmetic surgical instrument has been proven to transmit blood-borne diseases. Therefore, the syphilis in blood circulation should not be ignored.
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页数:8
相关论文
共 36 条
[1]  
Borobio M V, 1990, Enferm Infecc Microbiol Clin, V8, P7
[2]  
Brigette C, 2019, TREPONEMA PALLIDUM P, V14
[3]   ESTIMATING THE POPULATION ATTRIBUTABLE RISK FOR MULTIPLE RISK-FACTORS USING CASE-CONTROL DATA [J].
BRUZZI, P ;
GREEN, SB ;
BYAR, DP ;
BRINTON, LA ;
SCHAIRER, C .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1985, 122 (05) :904-913
[4]  
Choudhri Y, 2018, Can Commun Dis Rep, V44, P43, DOI 10.14745/ccdr.v44i02a02
[5]   Syphilis: Continuing public health and diagnostic challenges [J].
Daskalakis D. .
Current HIV/AIDS Reports, 2008, 5 (2) :72-77
[6]   The risk of transfusion-transmitted HIV from blood donations of men who have sex with men, 12 months after last sex with a man: 2005-2007 estimates from England and Wales [J].
Davison, K. L. ;
Conti, S. ;
Brailsford, S. R. .
VOX SANGUINIS, 2013, 105 (01) :85-88
[7]  
FARNES SW, 1990, POSTGRAD MED, V87, P37
[8]   Clinical diagnosis of syphilis: a ten-year retrospective analysis in a South Australian urban sexual health clinic [J].
Forrest, C. E. ;
Ward, A. .
INTERNATIONAL JOURNAL OF STD & AIDS, 2016, 27 (14) :1334-1337
[9]   Allowing blood donation from men who had sex with men more than 5years ago: a model to evaluate the impact on transfusion safety in Canada [J].
Germain, M. ;
Robillard, P. ;
Delage, G. ;
Goldman, M. .
VOX SANGUINIS, 2014, 106 (04) :372-375
[10]   Body appreciation, interest in cosmetic enhancements, and need for uniqueness among US college students [J].
Gillen, Meghan M. ;
Dunaev, Jamie .
BODY IMAGE, 2017, 22 :136-143