The Future of Childhood Cancer Survivorship Challenges and Opportunities for Continued Progress

被引：30

作者：

Dixon, Stephanie B. ^{[1
]}

Chow, Eric J. ^{[2
]}

Hjorth, Lars ^{[3
,4
]}

Hudson, Melissa M. ^{[5
]}

Kremer, Leontien C. M. ^{[6
,7
]}

Morton, Lindsay M. ^{[8
]}

Nathan, Paul C. ^{[9
]}

Ness, Kirsten K. ^{[10
]}

Oeffinger, Kevin C. ^{[11
]}

Armstrong, Gregory T. ^{[10
]}

机构：

[1] St Jude Childrens Res Hosp, Dept Oncol, MS 735,262 Danny Thomas Pl, Memphis, TN 38105 USA

[2] Univ Washington, Fred Hutchinson Canc Res Ctr, 1100 Fairview Ave North,M4-C308, Seattle, WA 98109 USA

[3] Skane Univ Hosp, Dept Paediat, Lund, Sweden

[4] Lund Univ, Clin Sci Lund, S-22185 Lund, Sweden

[5] St Jude Childrens Res Hosp, Dept Oncol, Div Canc Survivorship, MS 735,262 Danny Thomas Pl, Memphis, TN 38105 USA

[6] Princess Maxima Ctr, Heidelberglaan 25, NL-3584 CS Utrecht, Netherlands

[7] Emma Childrens Hosp, Amsterdam UMC, Amsterdam, Netherlands

[8] NCI, Radiat Epidemiol Branch, Div Canc Epidemiol & Genet, NIH, 9609 Med Ctr Dr,MSC 9778, Bethesda, MD 20892 USA

[9] Hosp Sick Children, Div Hematol Oncol, 555 Univ Ave,Room 9402 Black Wing, Toronto, ON M5G 1X8, Canada

[10] St Jude Childrens Res Hosp, Dept Epidemiol & Canc Control, MS 735,262 Danny Thomas Pl, Memphis, TN 38105 USA

[11] Duke Ctr Oncoprimary Care, Duke Canc Inst, 2424 Erwin Dr,Suite 601, Durham, NC 27705 USA

来源：

PEDIATRIC CLINICS OF NORTH AMERICA | 2020年 / 67卷 / 06期

关键词：

Adolescent; Cancer; Child; Delivery of health care; Neoplasms; Survivor; Treatment outcome; SUBSEQUENT MALIGNANT NEOPLASMS; ADULT SURVIVORS; STANDARD THERAPY; HEART-FAILURE; GENETIC RISK; MEDICAL-CARE; ASSOCIATION; IMPACT; PREDICTION; OZOGAMICIN;

D O I：

10.1016/j.pcl.2020.07.013

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

As treatment evolves and the population who survive childhood cancer ages and increases in number, researchers must use novel approaches to prevent, identify and mitigate adverse effects of treatment. Future priorities include collaborative efforts to pool large cohort data to improve detection of late effects, identify late effects of novel therapies, and determine the contribution of genetic factors along with physiologic and accelerated aging among survivors. This knowledge should translate to individual risk prediction and prevention strategies. Finally, we must utilize health services research and implementation science to improve adoption of survivorship care recommendations outside of specialized pediatric oncology centers. © 2020 Elsevier Inc.

引用

页码：1237 / 1251

页数：15

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