Avian Aspergillus fumigatus Strains Resistant to both Itraconazole and Voriconazole

被引：55

作者：

Beernaert, L. A. ^{[1
]}

Pasmans, F. ^{[1
]}

Van Waeyenberghe, L. ^{[1
]}

Dorrestein, G. M. ^{[2
]}

Verstappen, F. ^{[3
]}

Vercammen, F. ^{[4
]}

Haesebrouck, F. ^{[1
]}

Martel, A. ^{[1
]}

机构：

[1] Univ Ghent, Fac Vet Med, Dept Pathol Bacteriol & Avian Dis, B-9820 Merelbeke, Belgium

[2] Dutch Res Inst Birds & Exot Anim NOIVBD, Diagnost Pathol Lab, Veldhoven, Netherlands

[3] Vet Clin Hoofdstr, Driebergen, Netherlands

[4] Antwerp Zoo, Antwerp, Belgium

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2009年 / 53卷 / 05期

关键词：

IN-VITRO SUSCEPTIBILITY; CROSS-RESISTANCE; AMPHOTERICIN-B; POSACONAZOLE; CYP51A; SPP;

D O I：

10.1128/AAC.01492-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro susceptibilities of 59 avian Aspergillus fumigatus strains to amphotericin B, itraconazole, and voriconazole were determined using the standard microdilution broth method (CLSI M38-A2). Four isolates showed acquired resistance to itraconazole and voriconazole, harboring implications for the treatment of aspergillosis in both birds and humans.

引用

页码：2199 / 2201

页数：3

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