Thieme Chemistry Journal Awardees - Where are They Now? Dibutyltin Dimethoxide Catalyzed N-Nitrosoaldol Reaction of Alkenyl Trichloroacetate

被引：9

作者：

Yanagisawa, Akira ^{[1
]}

Izumi, Youhei ^{[2
]}

Takeshita, Satoshi ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Sci, Dept Chem, Inage Ku, Chiba 2638522, Japan

[2] Chiba Univ, Grad Sch Sci & Technol, Inage Ku, Chiba 2638522, Japan

来源：

SYNLETT | 2009年 / 05期

关键词：

tin catalyst; nitrosoaldol reaction; alpha-hydroxyamino ketone; alkenyl trichloroacetate; nitrosobenzene; ENANTIOSELECTIVE ALPHA-AMINOXYLATION; DIELS-ALDER REACTION; CARBONYL-COMPOUNDS; ORGANOCATALYTIC ROUTE; ENANTIOMERIC EXCESS; ALDOL SYNTHESIS; ALDOL/MICHAEL REACTION; ASYMMETRIC-SYNTHESIS; BRANCHED ALDEHYDES; AMINO-ALCOHOLS;

D O I：

10.1055/s-0028-1087815

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nitrosoaldol reaction between alkenyl trichloroacetates and nitrosobenzene has been achieved using dibutyltin dimethoxide as a catalyst, which is regenerated in the presence of methanol. The corresponding alpha-hydroxyamino ketones (N-adducts) have exclusively formed not only from cyclic alkenyl trichloroacetates but also from acyclic ones.

引用

页码：716 / 719

页数：4

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