Prophylactic total thyroidectomy using the minimally invasive video-assisted approach in children with multiple endocrine neoplasia type 2

被引:2
作者
Glynn, Ronan W. [1 ]
Cashman, Emma C. [1 ]
Doody, Jaime [1 ]
Phelan, Eimear [2 ]
Russell, John D. [2 ]
Timon, Conrad [1 ]
机构
[1] Royal Victoria Eye & Ear Hosp, Dept Otorhinolaryngol, Dublin 2, Ireland
[2] Our Ladys Childrens Hosp, Dept Otorhinolaryngol, Dublin, Ireland
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2014年 / 36卷 / 06期
关键词
MIVAT; MEN2; medullary thyroid cancer; RET; GUIDELINES ACCURATELY GUIDE; RET PROTOONCOGENE; HEREDITARY; CARCINOMA; ASSOCIATION; CANCER; MANAGEMENT; PHENOTYPE; GENOTYPE; SURGERY;
D O I
10.1002/hed.23358
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
BackgroundThere have been few reports of prophylactic thyroidectomy using the minimally invasive video-assisted thyroidectomy (MIVAT) approach in children with multiple endocrine neoplasia 2 (MEN2). MethodsWe conducted a retrospective review of a prospectively maintained database of patients who underwent MIVAT for total thyroidectomy. ResultsSix children underwent MIVAT; RET codon mutations identified were 634, 620, 611, and 918. Mean operative time was 93 minutes (range, 68-105 minutes). Five patients were discharged on the first postoperative day; however, 1 patient had a postoperative hematoma and was discharged 2 days postoperatively. There were no cases of laryngeal nerve palsy or postoperative hypoparathyroidism. High levels of satisfaction with postoperative cosmesis were reported. Calcitonin levels have been undetectable at follow-up thus far (mean follow-up, 42.8 months). ConclusionAlthough our outcomes are similar to those reported using the traditional approach, it is important to note that MIVAT is essentially the same operation, just performed through a smaller incision, with resulting benefits in terms of pain, cosmesis and, perhaps, morbidity. (c) 2013 Wiley Periodicals, Inc. Head Neck 36: 768-771, 2014
引用
收藏
页码:768 / 771
页数:4
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