8,9,10,10a-tetrahydro-6H-tetrazolo[1,5-a]pyrrolo[2,1-c]pyrazines:: New heterocyclic frameworks generated by an Ugi-type multicomponent reaction

被引：19

作者：

Franckevicius, Vilius ^{[1
]}

Longbottom, Deborah A. ^{[1
]}

Turner, Richard M. ^{[1
]}

Ley, Steven V. ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

来源：

SYNTHESIS-STUTTGART | 2006年 / 19期

关键词：

multicomponent reactions; heterocycles; tetrazole; Ugi reaction; proline derivatives;

D O I：

10.1055/s-2006-950219

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot, Ugi-type three-component coupling process between an aldehyde, an isocyanide and proline tetrazole is reported, leading to new heterocyclic structures in good to excellent yields.

引用

页码：3215 / 3223

页数：9

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