Implications of Necroptosis for Cardiovascular Diseases

被引：37

作者：

Ruan, Zhao-hui ^{[1
]}

Xu, Zi-xuan ^{[1
]}

Zhou, Xue-yun ^{[1
]}

Zhang, Xian ^{[1
]}

Shang, Lei ^{[1
]}

机构：

[1] Nanchang Univ, Affiliated Eye Hosp, Jiangxi Res Inst Ophthalmol & Visual Sci, Nanchang 330006, Jiangxi, Peoples R China

来源：

CURRENT MEDICAL SCIENCE | 2019年 / 39卷 / 04期

关键词：

cell death; death-associated molecular patterns; necroptosis; cardiovascular disease; MIXED LINEAGE KINASE; LOW-DENSITY-LIPOPROTEIN; DOMAIN-LIKE PROTEIN; CELL-DEATH; PROGRAMMED NECROSIS; APOPTOSIS; RIP3; ATHEROSCLEROSIS; CARDIOMYOCYTES; INFLAMMATION;

D O I：

10.1007/s11596-019-2067-6

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Necroptosis is a non-apoptotic programmed cell death pathway, which causes necrosis-like morphologic changes and triggers inflammation in the surrounding tissues. Accumulating evidence has demonstrated that necroptosis is involved in a number of pathological processes that lead to cardiovascular diseases. However, the exact molecular pathways linking them remain unknown. Herein, this review summarizes the necroptosis-related pathways involved in the development of various cardiovascular diseases, including atherosclerosis, cardiac ischemia-reperfusion injury, cardiac hypertrophy, dilated cardiomyopathy and myocardial infarction, and may shed light on the diagnosis and treatment of these diseases.

引用

页码：513 / 522

页数：10

共 70 条

[1] Cardiorespiratory Fitness and Cardiovascular Disease Prevention: an Update [J].

Al-Mallah, Mouaz H. ;

Sakr, Sherif ;

Al-Qunaibet, Ada .

CURRENT ATHEROSCLEROSIS REPORTS, 2018, 20 (01)

[2] Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2 [J].

Alvarez, Sergio E. ;

Harikumar, Kuzhuvelil B. ;

Hait, Nitai C. ;

Allegood, Jeremy ;

Strub, Graham M. ;

Kim, Eugene Y. ;

Maceyka, Michael ;

Jiang, Hualiang ;

Luo, Cheng ;

Kordula, Tomasz ;

Milstien, Sheldon ;

Spiegel, Sarah .

NATURE, 2010, 465 (7301) :1084-U149

[3] cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination [J].

Bertrand, Mathieu J. M. ;

Milutinovic, Snezana ;

Dickson, Kathleen M. ;

Ho, Wai Chi ;

Boudreault, Alain ;

Durkin, Jon ;

Gillard, John W. ;

Jaquith, James B. ;

Morris, Stephen J. ;

Barker, Philip A. .

MOLECULAR CELL, 2008, 30 (06) :689-700

[4]

Brunvand Harald, 2003, Tidsskr Nor Laegeforen, V123, P930

[5]

Carden DL, 2000, J PATHOL, V190, P255, DOI 10.1002/(SICI)1096-9896(200002)190:3<255::AID-PATH526>3.0.CO

[6]

2-6

[7] Cardiac Specific Knockout of p53 Decreases ER Stress-Induced Mitochondrial Damage [J].

Chen, Qun ;

Thompson, Jeremy ;

Hu, Ying ;

Das, Anindita ;

Lesnefsky, Edward J. .

FRONTIERS IN CARDIOVASCULAR MEDICINE, 2019, 6

[8] Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death [J].

Chen, Xin ;

Li, Wenjuan ;

Ren, Junming ;

Huang, Deli ;

He, Wan-ting ;

Song, Yunlong ;

Yang, Chao ;

Li, Wanyun ;

Zheng, Xinru ;

Chen, Pengda ;

Han, Jiahuai .

CELL RESEARCH, 2014, 24 (01) :105-121

[9] Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation [J].

Cho, YoungSik ;

Challa, Sreerupa ;

Moquin, David ;

Genga, Ryan ;

Ray, Tathagat Dutta ;

Guildford, Melissa ;

Chan, Francis Ka-Ming .

CELL, 2009, 137 (06) :1112-1123

[10]

Dargel R, 1989, Z Med Lab Diagn, V30, P251

← 1 2 3 4 5 6 7 →