Cannabis improves night vision: a case study of dark adaptometry and scotopic sensitivity in kif smokers of the Rif mountains of northern Morocco

被引:37
作者
Russo, EB
Merzouki, A
Mesa, JM
Frey, KA
Bach, P
机构
[1] Univ Granada, Fac Pharm, Dept Bot, E-18071 Granada, Spain
[2] Univ Abdelmalek Essaadi, Fac Sci, Lab Ethnobot, Tetouan, Morocco
[3] Montana State Univ, Sch Nursing, Missoula, MT 59812 USA
[4] Montana Neurobehav Specialists, Missoula, MT 59802 USA
关键词
cannabis; medical marijuana; Ethnobotany; night vision; ophthalmology; visual testing;
D O I
10.1016/j.jep.2004.03.029
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Previous reports have documented an improvement in night vision among Jamaican fishermen after ingestion of a crude tincture of herbal cannabis, while two members of this group noted that Moroccan fishermen and mountain dwellers observe an analogous improvement after smoking kif, sifted Cannabis sativa mixed with tobacco (Nicotiana rustica). Field-testing of night vision has become possible with a portable device, the LKC Technologies Scotopic Sensitivity Tester-1 (SST-1). This study examines the results of double-blinded graduated THC administration 0-20 mg (as Marinol(R)) versus placebo in one subject on measures of dark adaptometry and scotopic sensitivity. Analogous field studies were per-formed in Morocco with the SST-1 in three subjects before and after smoking kif. In both test situations, improvements in night vision measures were noted after THC or cannabis. It is believed that this effect is dose-dependent and cannabinoid-mediated at the retinal level. Further testing may assess possible clinical application of these results in retinitis pigmentosa or other conditions. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:99 / 104
页数:6
相关论文
共 32 条
  • [1] ABBOTTJOHNSON W, 2002, CELL BIOL, V680, pA2
  • [2] [Anonymous], PAIN MANAGEMENT PRAC
  • [3] [Anonymous], STUDIES HIST MED
  • [4] Arnold S, 1998, Nurs Stand, V12, P17
  • [5] Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina
    Bisogno, T
    Delton-Vandenbroucke, I
    Milone, A
    Lagarde, M
    Di Marzo, V
    [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1999, 370 (02) : 300 - 307
  • [6] PUPIL SIZE AFTER USE OF MARIHUANA AND ALCOHOL
    BROWN, B
    ADAMS, AJ
    HAEGERSTROMPORTNOY, G
    JONES, RT
    FLOM, MC
    [J]. AMERICAN JOURNAL OF OPHTHALMOLOGY, 1977, 83 (03) : 350 - 354
  • [7] CLARK RC, 1998, HASHISH RED EYE
  • [8] DAWSON WW, 1977, INVEST OPHTH VIS SCI, V16, P689
  • [9] Cannabinoid receptors in the human brain: A detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain
    Glass, M
    Dragunow, M
    Faull, RLM
    [J]. NEUROSCIENCE, 1997, 77 (02) : 299 - 318
  • [10] A WHOLE-FIELD SCOTOPIC RETINAL SENSITIVITY TEST FOR THE DETECTION OF EARLY GLAUCOMA DAMAGE
    GLOVINSKY, Y
    QUIGLEY, HA
    DRUM, B
    BISSETT, RA
    JAMPEL, HD
    [J]. ARCHIVES OF OPHTHALMOLOGY, 1992, 110 (04) : 486 - 490