New perspectives on screening and early detection of endometrial cancer

被引：72

作者：

Costas, Laura ^{[1
]}

Frias-Gomez, Jon ^{[1
]}

Guardiola, Magdalena ^{[1
]}

Benavente, Yolanda ^{[1
,2
]}

Pineda, Marta ^{[3
]}

Pavon, Miquel A. ^{[1
,4
]}

Martinez, Jose M. ^{[5
]}

Climent, Maite ^{[5
]}

Barahona, Marc ^{[5
]}

Canet, Julia ^{[3
]}

Paytubi, Sonia ^{[1
]}

Salinas, Monica ^{[3
]}

Palomero, Luis ^{[6
]}

Bianchi, Ilaria ^{[7
]}

Reventos, Jaume ^{[8
]}

Capella, Gabriel ^{[3
,4
]}

Diaz, Mireia ^{[1
,4
]}

Vidal, August ^{[4
,9
]}

Piulats, Josep M. ^{[4
,10
]}

Aytes, Alvaro ^{[6
]}

Ponce, Jordi ^{[5
]}

Brunet, Joan ^{[3
,4
,11
]}

Bosch, Francesc X. ^{[1
,4
]}

Matias-Guiu, Xavier ^{[4
,9
]}

Alemany, Laia ^{[1
,2
]}

de Sanjose, Silvia ^{[2
,12
]}

机构：

[1] Catalan Inst Oncol, IDIBELL, Canc Epidemiol Res Programme, Barcelona, Spain

[2] CIBERESP, Consortium Biomed Res Epidemiol & Publ Hlth, Madrid, Spain

[3] Catalan Inst Oncol, IDIBELL, Hereditary Canc Program, Barcelona, Spain

[4] Ctr Invest Biomed Red Canc CIBERONC, Madrid, Spain

[5] Hosp Univ Bellvitge, IDIBELL, Dept Gynecol & Obstet, Barcelona, Spain

[6] Catalan Inst Oncol, IDIBELL, Program Canc Therapeut Resistance ProCURE, Barcelona, Spain

[7] SAP Delta Llobregat, ASSIR Delta, Direccio Atencio Primaria Costa Ponent, Barcelona, Spain

[8] Univ Int Catalunya, Dept Ciencies Basiques, Barcelona, Spain

[9] Hosp Univ Bellvitge, Dept Pathol, IDIBELL, Barcelona, Spain

[10] Catalan Inst Canc, IDIBELL, Dept Med Oncol, Barcelona, Spain

[11] Univ Girona, Sch Med, Med Sci Dept, Girona, Spain

[12] PATH, Seattle, WA USA

来源：

INTERNATIONAL JOURNAL OF CANCER | 2019年 / 145卷 / 12期

关键词：

endometrial cancer; early detection; screening; pap smears; genomics; biomarkers; LYNCH SYNDROME; BREAST-CANCER; DNA METHYLATION; ASYMPTOMATIC WOMEN; PREDICTION MODELS; ADJUVANT BREAST; EARLY-DIAGNOSIS; RISK; CARCINOMA; HYPERPLASIA;

D O I：

10.1002/ijc.32514

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Due to the anatomical continuity of the uterine cavity with the cervix, genomic exploitation of material from routine Pap smears and other noninvasive sampling methods represent a unique opportunity to detect signs of disease using biological material shed from the upper genital tract. Recent research findings offer a promising perspective in the detection of endometrial cancer, but certain questions need to be addressed in order to accelerate the implementation of novel technologies in a routine screening or clinical setting. We discuss here new perspectives on detection of endometrial cancer using genomic and other biomarkers in minimally invasive sampling methods with a special focus on public health classic screening criteria, highlighting current gaps in knowledge.

引用

页码：3194 / 3206

页数：13

共 114 条

[1] Prediction models for endometrial cancer for the general population or symptomatic women: A systematic review [J].

Alblas, Maaike ;

Velt, Kimberley B. ;

Pashayan, Nora ;

Widschwendter, Martin ;

Steyerberg, Ewout W. ;

Vergouwe, Yvonne .

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2018, 126 :92-99

[2] Contribution of cervical cytology in the diagnostic work-up of patients with endometrial cancer [J].

Amkreutz, L. C. M. ;

Pijnenborg, J. M. A. ;

Joosten, D. W. L. ;

Mertens, H. J. M. M. ;

Van Kuijk, S. M. J. ;

Engelen, M. J. A. ;

Bergmans, M. ;

Nolting, W. E. ;

Kruitwagen, R. F. P. M. .

CYTOPATHOLOGY, 2018, 29 (01) :63-70

[3] Revisiting Wilson and Jungner in the genomic age:: a review of screening criteria over the past 40 years [J].

Andermann, Anne ;

Blancquaert, Ingeborg ;

Beauchamp, Sylvie ;

Dery, Veronique .

BULLETIN OF THE WORLD HEALTH ORGANIZATION, 2008, 86 (04) :317-319

[4] George Papanicolaou's Efforts to Develop Novel Cytologic Methods for the Early Diagnosis of Endometrial Carcinoma [J].

Austin, R. Marshall .

ACTA CYTOLOGICA, 2017, 61 (4-5) :281-298

[5] The molecular genetics and morphometry-based Endometrial Intraepithelial Neoplasia classification system predicts disease progression in Endometrial hyperplasia more accurately than the 1994 World Health Organization classification system [J].

Baak, JP ;

Mutter, GL ;

Robboy, S ;

van Diest, PJ ;

Uyterlinde, AM ;

Orbo, A ;

Palazzo, J ;

Fiane, B ;

Lovslett, K ;

Burger, C ;

Voorhorst, F ;

Verheijen, RH .

CANCER, 2005, 103 (11) :2304-2312

[6] Novel approaches to early detection of endometrial cancer [J].

Bagaria, Madhu ;

Shields, Emily ;

Bakkum-Gamez, Jamie N. .

CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, 2017, 29 (01) :40-46

[7] Detection of endometrial cancer via molecular analysis of DNA collected with vaginal tampons [J].

Bakkum-Gamez, Jamie N. ;

Wentzensen, Nicolas ;

Maurer, Matthew L. ;

Hawthorne, Kieran M. ;

Voss, Jesse S. ;

Kroneman, Trynda N. ;

Famuyide, Abimbola O. ;

Clayton, Amy C. ;

Hailing, Kevin C. ;

Kerr, Sarah E. ;

Cliby, William A. ;

Dowdy, Sean C. ;

Kipp, Benjamin R. ;

Mariani, Andrea ;

Oberg, Ann L. ;

Podratz, Karl C. ;

Shridhar, Viji ;

Sherman, Mark E. .

GYNECOLOGIC ONCOLOGY, 2015, 137 (01) :14-22

[8] Familial risk-colorectal cancer: ESMO Clinical Practice Guidelines [J].

Balmana, J. ;

Balaguer, F. ;

Cervantes, A. ;

Arnold, D. .

ANNALS OF ONCOLOGY, 2013, 24 :73-80

[9] Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients [J].

Berg, Anna ;

Hoivik, Erling A. ;

Mjos, Siv ;

Holst, Frederik ;

Werner, Henrica M. J. ;

Tangen, Ingvild L. ;

Taylor-Weiner, Amaro ;

Gibson, William J. ;

Kusonmano, Kanthida ;

Wik, Elisabeth ;

Trovik, Jone ;

Halle, Mari K. ;

Oyan, Anne M. ;

Kalland, Karl-Henning ;

Cherniack, Andrew D. ;

Beroukhim, Rameen ;

Stefansson, Ingunn ;

Mills, Gordon B. ;

Krakstad, Camilla ;

Salvesen, Helga B. .

ONCOTARGET, 2015, 6 (02) :1327-1339

[10] Estimating the Risk of Endometrial Cancer in Symptomatic Postmenopausal Women A Novel Clinical Prediction Model Based on Patients' Characteristics [J].

Burbos, Nikolaos ;

Musonda, Patrick ;

Duncan, Timothy J. ;

Crocker, Simon G. ;

Morris, Edward P. ;

Nieto, Joaquin J. .

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2011, 21 (03) :500-506

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