Chipping Away at Blood-Brain-Barrier Modeling

被引：3

作者：

Jamieson, John J. ^{[1
,2
]}

Gerecht, Sharon ^{[1
,2
,3
,4
]}

机构：

[1] Johns Hopkins Univ, Dept Chem & Biomol Engn, Baltimore, MD 21218 USA

[2] Johns Hopkins Univ, Inst NanoBioTechnol, Baltimore, MD 21218 USA

[3] Johns Hopkins Univ, Dept Biomed Engn, Baltimore, MD 21218 USA

[4] Johns Hopkins Univ, Dept Mat Sci & Engn, Baltimore, MD 21218 USA

来源：

CELL STEM CELL | 2019年 / 24卷 / 06期

关键词：

ENDOTHELIAL-CELLS;

D O I：

10.1016/j.stem.2019.05.014

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

In this issue, Vatine et al. (2019) present a fully human blood-brain barrier chip that accurately predicts drug permeability and can be perfused with whole blood. Utilizing patient-derived tissue, they recapitulate disease-specific defects and establish a platform to advance drug screening and disease modeling.

引用

页码：831 / 832

页数：2

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