Magnetic immunoassay based on frequency mixing magnetic detection and magnetic particles of different magnetic properties

被引:8
作者
Hong, H. B. [1 ]
Krause, H. -J. [2 ]
Nam, I. H. [3 ]
Choi, C. J. [4 ]
Shin, S. W. [1 ]
机构
[1] ETRI, IT Convergence Res Lab, Taejon 307700, South Korea
[2] Forschungszentrum Julich, PGI 8, D-52425 Julich, Germany
[3] Korea Inst Geosci & Mineral Resources KIGAM, Geol Hazards Div, Taejon 305350, South Korea
[4] Chonbuk Natl Univ, Dept BIN Fus Technol, Jeonju 561756, South Korea
关键词
BIOSENSOR; PURIFICATION;
D O I
10.1039/c4ay01283f
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A novel analytical system is presented that employs two different types of magnetic particles (MPs) with frequency mixing magnetic detection (FMMD). A model experiment with MPs and FMMD demonstrates that this method significantly reduces the steps involved in common immunobiological assays and enables repetition of the measurement without signal decay.
引用
收藏
页码:8055 / 8058
页数:4
相关论文
共 22 条
[1]  
[Anonymous], BIOMEMS BIOMEDICAL N
[2]   Magnetic particles for the separation and purification of nucleic acids [J].
Berensmeier, Sonja .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2006, 73 (03) :495-504
[3]   Ultrasensitive magnetic biosensor for homogeneous immunoassay [J].
Chemla, YR ;
Crossman, HL ;
Poon, Y ;
McDermott, R ;
Stevens, R ;
Alper, MD ;
Clarke, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (26) :14268-14272
[4]   High-throughput lectin magnetic bead array-coupled tandem mass spectrometry for glycoprotein biomarker discovery [J].
Choi, Eunju ;
Loo, Dorothy ;
Dennis, James W. ;
O'Leary, Caroline A. ;
Hill, Michelle M. .
ELECTROPHORESIS, 2011, 32 (24) :3564-3575
[5]   Monodisperse magnetic nanoparticles for biodetection, imaging, and drug delivery: a versatile and evolving technology [J].
Dave, Shivang R. ;
Gao, Xiaohu .
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 2009, 1 (06) :583-609
[6]   Protein purification using magnetic adsorbent particles [J].
Franzreb, M ;
Siemann-Herzberg, M ;
Hobley, TJ ;
Thomas, ORT .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2006, 70 (05) :505-516
[7]   Tomographic imaging using the nonlinear response of magnetic particles [J].
Gleich, B ;
Weizenecker, R .
NATURE, 2005, 435 (7046) :1214-1217
[8]   X-Space MPI: Magnetic Nanoparticles for Safe Medical Imaging [J].
Goodwill, Patrick William ;
Saritas, Emine Ulku ;
Croft, Laura Rose ;
Kim, Tyson N. ;
Krishnan, Kannan M. ;
Schaffer, David V. ;
Conolly, Steven M. .
ADVANCED MATERIALS, 2012, 24 (28) :3870-3877
[9]   Magnetic nanoparticle detection using nano-SQUID sensors [J].
Hao, L. ;
Cox, D. ;
See, P. ;
Gallop, J. ;
Kazakova, O. .
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2010, 43 (47)
[10]   Detection of two different influenza A viruses using a nitrocellulose membrane and a magnetic biosensor [J].
Hong, Hyo-Bong ;
Krause, Hans-Joachim ;
Song, Ki-Bong ;
Choi, Chel-Jong ;
Chung, Myung-Ae ;
Son, Sung-won ;
Offenhaeusser, Andreas .
JOURNAL OF IMMUNOLOGICAL METHODS, 2011, 365 (1-2) :95-100