Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex

被引：148

作者：

Chen, Xing ^{[1
]}

Wang, Feng ^{[1
]}

Fernandez, Eduardo ^{[2
,3
]}

Roelfsema, Pieter R. ^{[1
,4
,5
]}

机构：

[1] Netherlands Inst Neurosci, Dept Vis & Cognit, Meibergdreef 47, NL-1105 BA Amsterdam, Netherlands

[2] Miguel Hernandez Univ Elche, Bioengn Inst, Elche, Spain

[3] Miguel Hernandez Univ Elche, CIBER BBN, Elche, Spain

[4] Vrije Univ Amsterdam, Dept Integrat Neurophysiol, De Boelelaan 1085, NL-1081 HV Amsterdam, Netherlands

[5] Acad Med Ctr, Dept Psychiat, Postbus 22660, NL-1100 DD Amsterdam, Netherlands

来源：

SCIENCE | 2020年 / 370卷 / 6521期

关键词：

D O I：

10.1126/science.abd7435

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Blindness affects 40 million people across the world. A neuroprosthesis could one day restore functional vision in the blind. We implanted a 1024-channel prosthesis in areas V1 and V4 of the visual cortex of monkeys and used electrical stimulation to elicit percepts of dots of light (called phosphenes) on hundreds of electrodes, the locations of which matched the receptive fields of the stimulated neurons. Activity in area V4 predicted phosphene percepts that were elicited in V1. We simultaneously stimulated multiple electrodes to impose visible patterns composed of a number of phosphenes. The monkeys immediately recognized them as simple shapes, motions, or letters. These results demonstrate the potential of electrical stimulation to restore functional, life-enhancing vision in the blind.

引用

页码：1191 / 1196

页数：6

共 41 条

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