Steroidal saponins from dragon's blood of Dracaena cambodiana

被引：26

作者：

Shen, Hai-Yan ^{[1
,2
]}

Zuo, Wen-Jian ^{[1
]}

Wang, Hui ^{[1
]}

Zhao, You-Xing ^{[1
]}

Guo, Zhi-Kai ^{[1
]}

Luo, Ying ^{[1
]}

Li, Xiao-Na ^{[1
]}

Dai, Hao-Fu ^{[1
]}

Mei, Wen-Li ^{[1
]}

机构：

[1] Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Hainan, Peoples R China

[2] Hainan Univ, Hort & Garden Coll, Haikou 570228, Peoples R China

来源：

FITOTERAPIA | 2014年 / 94卷

关键词：

Dracaena cambodiana (Agavaceae); Dragon's blood; Steroidal saponins; Cytotoxicity; FRESH STEMS; GLYCOSIDES; RHIZOMES;

D O I：

10.1016/j.fitote.2014.01.020

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Six new steroidal saponins, cambodianosides A-F (1-6), together with seven known ones, were isolated from the dragon's blood of Dracaena cambodiana. The structures of 1-6 were elucidated on the basis of detailed spectroscopic analysis, including 1D and 2D NMR techniques and chemical methods. The cytotoxicities of all the isolated compounds were evaluated in vitro against three human cancer cell lines, and compounds 7, 8, and 11 showed significant inhibitory activities. Crown Copyright (C) 2014 Published by Elsevier B.V. All rights reserved.

引用

页码：94 / 101

页数：8

共 31 条

[1] Assigning stereodiversity of the 27-Me group of furostane-type steroidal saponins via NMR chemical shifts [J].