Twenty years of boosting antiretroviral agents: where are we today?

被引:11
作者
Boffito, Marta [1 ,2 ]
Back, David [3 ]
Gatell, Jose M. [4 ,5 ,6 ]
机构
[1] Chelsea & Westminster Hosp, St Stephens AIDS Trust, London SW10 9NH, England
[2] Univ London Imperial Coll Sci Technol & Med, London, England
[3] Univ Liverpool, Liverpool L69 3BX, Merseyside, England
[4] Hosp Clin Barcelona, IDIBAPS, Infect Dis Unit, Barcelona, Spain
[5] Hosp Clin Barcelona, IDIBAPS, AIDS Unit, Barcelona, Spain
[6] Univ Barcelona, Barcelona, Spain
关键词
boosted integrase inhibitors; boosted protease inhibitors; LOW-DOSE RITONAVIR; REVERSE-TRANSCRIPTASE INHIBITOR; TENOFOVIR DISOPROXIL FUMARATE; NAIVE HIV-1-INFECTED PATIENTS; CO-FORMULATED ELVITEGRAVIR; HIV-INFECTED PATIENTS; PROTEASE INHIBITOR; OPEN-LABEL; INITIAL TREATMENT; COFORMULATED ELVITEGRAVIR;
D O I
10.1097/QAD.0000000000000800
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:2229 / 2233
页数:5
相关论文
共 50 条
[1]  
[Anonymous], 54 INT C ANT AG CHEM
[2]  
[Anonymous], 12 INT WORKSH CLIN P
[3]   Simplification to coformulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus continuation of ritonavir-boosted protease inhibitor with emtricitabine and tenofovir in adults with virologically suppressed HIV (STRATEGY-PI): 48 week results of a randomised, open-label, phase 3b, non-inferiority trial [J].
Arribas, Jose R. ;
Pialoux, Gilles ;
Gathe, Joseph ;
Di Perri, Giovanni ;
Reynes, Jacques ;
Tebas, Pablo ;
Thai Nguyen ;
Ebrahimi, Ramin ;
White, Kirsten ;
Piontkowsky, David .
LANCET INFECTIOUS DISEASES, 2014, 14 (07) :581-589
[4]   A meta-analysis of the efficacy and safety of unboosted atazanavir compared with ritonavir-boosted protease inhibitor maintenance therapy in HIV-infected adults with established virological suppression after induction [J].
Baril, J. ;
Conway, B. ;
Giguere, P. ;
Ferko, N. ;
Hollmann, S. ;
Angel, J. B. .
HIV MEDICINE, 2014, 15 (05) :301-310
[5]   New Approaches to Antiretroviral Drug Delivery: Challenges and Opportunities Associated with the Use of Long-Acting Injectable Agents [J].
Boffito, Marta ;
Jackson, Akil ;
Owen, Andrew ;
Becker, Stephen .
DRUGS, 2014, 74 (01) :7-13
[6]  
Boyd MA, 2013, LANCET, V381, P2091, DOI 10.1016/S0140-6736(13)61164-2
[7]  
Cameron DW, 1999, AIDS, V13, P213, DOI 10.1097/00002030-199902040-00009
[8]   Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells [J].
Cavet, ME ;
West, M ;
Simmons, NL .
BRITISH JOURNAL OF PHARMACOLOGY, 1996, 118 (06) :1389-1396
[9]   Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2:: a pooled subgroup analysis of data from two randomised trials [J].
Clotet, Bonaventura ;
Bellos, Nicholas ;
Molina, Jean-Michel ;
Cooper, David ;
Goffard, Jean-Chrostophe ;
Lazzarin, Adriano ;
Woehrmann, Andrej ;
Katlama, Christine ;
Wilkin, Timothy ;
Haubrich, Richard ;
Cohen, Calvin ;
Farthing, Charles ;
Jayaweera, Dushyantha ;
Markowitz, Martin ;
Ruane, Peter ;
Spinosa-Guzman, Sabrina ;
Lefebvre, Eric .
LANCET, 2007, 369 (9568) :1169-1178
[10]   Impact of Different Low-Dose Ritonavir Regimens on Lipids, CD36, and Adipophilin Expression [J].
Collot-Teixeira, S. ;
De Lorenzo, F. ;
Waters, L. ;
Fletcher, C. ;
Back, D. ;
Mandalia, S. ;
Pozniak, A. ;
Yilmaz, S. ;
McGregor, J. L. ;
Gazzard, B. ;
Boffito, M. .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2009, 85 (04) :375-378