Synthesis of low-molecular weight chiral compounds for fragment-based lead discovery

被引:0
|
作者
Nelson, Shawn [1 ,2 ]
Furst, Laura [2 ]
Haftchenary, Sina [1 ,2 ]
Ferrara, Steven [2 ]
Boskovic, Zarko [1 ,2 ]
Dandapani, Sivaraman [2 ]
Schreiber, Stuart [1 ,2 ]
机构
[1] Harvard Univ, Chem & Chem Biol, Cambridge, MA 02138 USA
[2] Broad Inst Harvard & MIT, Cambridge, MA USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
491
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Fragment-based lead discovery
    David C. Rees
    Miles Congreve,
    Christopher W. Murray
    Robin Carr
    Nature Reviews Drug Discovery, 2004, 3 : 660 - 672
  • [2] Fragment-Based Lead Discovery
    Davis, Ben J.
    Roughley, Stephen D.
    ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 50: PLATFORM TECHNOLOGIES IN DRUG DISCOVERY AND VALIDATION, 2017, 50 : 371 - 439
  • [3] Fragment-Based Lead Discovery
    Congreve, Miles
    Murray, Christopher W.
    Carr, Robin
    Rees, David C.
    ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 42, 2007, 42 : 431 - 448
  • [4] Fragment-based lead discovery
    Rees, DC
    Congreve, M
    Murray, CW
    Carr, R
    NATURE REVIEWS DRUG DISCOVERY, 2004, 3 (08) : 660 - 672
  • [5] Fragment-Based Lead Discovery and Design
    Joseph-McCarthy, Diane
    Campbell, Arthur J.
    Kern, Gunther
    Moustakas, Demetri
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2014, 54 (03) : 693 - 704
  • [6] EXPERIENCES IN FRAGMENT-BASED LEAD DISCOVERY
    Hubbard, Roderick E.
    Murray, James B.
    FRAGMENT-BASED DRUG DESIGN: TOOLS, PRACTICAL APPROACHES, AND EXAMPLES, 2011, 493 : 509 - 531
  • [7] Fragment-based lead discovery grows up
    Monya Baker
    Nature Reviews Drug Discovery, 2013, 12 : 5 - 7
  • [8] A rule of three for fragment-based lead discovery?
    Congreve, M
    Carr, R
    Murray, C
    Jhoti, H
    DRUG DISCOVERY TODAY, 2003, 8 (19) : 876 - 877
  • [9] Fragment-based lead discovery: leads by design
    Carr, RAE
    Congreve, M
    Murray, CW
    Rees, DC
    DRUG DISCOVERY TODAY, 2005, 10 (14) : 987 - 992
  • [10] Case studies in fragment-based lead discovery
    Congreve, MS
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U2763 - U2763