Taming the Carboxyl Group for Directed Carbometalation: Observations on the Use of Anions, Dianions and Ester Enolates

被引：2

作者：

Desrat, Sandy ^{[1
]}

Gray, Philip J. ^{[1
]}

Penny, Matthew R. ^{[1
]}

Motherwell, William B. ^{[1
]}

机构：

[1] UCL, Dept Chem, London WC1H 0AJ, England

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2014年 / 20卷 / 29期

关键词：

allene; carbometalation; copper; enolate; Grignard reagent; MEDIATED CARBOMETALLATION; GRIGNARD-REAGENTS; ALKYNES; DERIVATIVES; ALLENES; CARBOCUPRATION; 2,3-ALLENOLS; CATALYSIS; CHLORIDE; ALKENES;

D O I：

10.1002/chem.201403294

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Carboxylate anions, dianions and ester enolates provide simultaneous protection and activation for directed carbometalation reactions. Advantage can be taken of the bis-carbanionic character of the intermediate for further controlled C-C bond forming reactions.

引用

收藏

页码：8918 / 8922

页数：5

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