T-2*;
Cortex;
Biomarker;
Cytoarchitecture;
Myeloarchitecture;
Brodmann;
HUMAN AUDITORY-CORTEX;
HIGH-RESOLUTION MRI;
HIGH-FIELD MRI;
IN-VIVO VISUALIZATION;
HUMAN CEREBRAL-CORTEX;
NMR RELAXATION-TIMES;
HUMAN BRAIN;
MYELIN WATER;
T;
MULTIPLE-SCLEROSIS;
D O I:
10.1016/j.neuroimage.2013.01.023
中图分类号:
Q189 [神经科学];
学科分类号:
071006 ;
摘要:
Studies have shown that T-2* contrast can reveal features of cortical anatomy. However, understanding the relationship between T-2* contrast and the underlying cyto- and myelo-architecture is not an easy task, given the number of confounds, such as myelin, iron, blood vessels and structure orientation. Moreover, it is difficult to obtain reliable T-2* measurements in the cortex due to its thin and folded geometry and the presence of artifacts. This review addresses issues associated with T-2* mapping in the human cortex. After describing the theory behind T-2* relaxation, a list of practical steps is proposed to reliably acquire and process T-2* data and then map these values within the cortex using surface-based analysis. The last section addresses the question: "What can we gain from T-2* cortical mapping?", with particular emphasis on Brodmann mapping. (C) 2013 Elsevier Inc. All rights reserved.
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页码:189 / 200
页数:12
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机构:
Tel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, IsraelTel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, Israel
Assaf, Yaniv
Blumenfeld-Katzir, Tamar
论文数: 0引用数: 0
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机构:
Tel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, IsraelTel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, Israel
Blumenfeld-Katzir, Tamar
Yovel, Yossi
论文数: 0引用数: 0
h-index: 0
机构:
Tel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, IsraelTel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, Israel
Yovel, Yossi
Basser, Peter J.
论文数: 0引用数: 0
h-index: 0
机构:
NICHHD, Sect Tissue Biophys & Biomimet, Lab Integrated Med Biophys, Natl Inst Hlth, Bethesda, MD 20892 USATel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, Israel
机构:
Tel Aviv Univ, Dept Neurobiol, George S Wise Fac Life Sci, IL-69978 Tel Aviv, IsraelTel Aviv Univ, Dept Neurobiol, George S Wise Fac Life Sci, IL-69978 Tel Aviv, Israel
Barazany, Daniel
Assaf, Yaniv
论文数: 0引用数: 0
h-index: 0
机构:
Tel Aviv Univ, Dept Neurobiol, George S Wise Fac Life Sci, IL-69978 Tel Aviv, IsraelTel Aviv Univ, Dept Neurobiol, George S Wise Fac Life Sci, IL-69978 Tel Aviv, Israel
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Bilgic, Berkin
Pfefferbaum, Adolf
论文数: 0引用数: 0
h-index: 0
机构:
Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford, CA 94305 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Pfefferbaum, Adolf
Rohlfing, Torsten
论文数: 0引用数: 0
h-index: 0
机构:MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Rohlfing, Torsten
Sullivan, Edith V.
论文数: 0引用数: 0
h-index: 0
机构:
Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford, CA 94305 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Sullivan, Edith V.
Adalsteinsson, Elfar
论文数: 0引用数: 0
h-index: 0
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
机构:
Tel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, IsraelTel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, Israel
Assaf, Yaniv
Blumenfeld-Katzir, Tamar
论文数: 0引用数: 0
h-index: 0
机构:
Tel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, IsraelTel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, Israel
Blumenfeld-Katzir, Tamar
Yovel, Yossi
论文数: 0引用数: 0
h-index: 0
机构:
Tel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, IsraelTel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, Israel
Yovel, Yossi
Basser, Peter J.
论文数: 0引用数: 0
h-index: 0
机构:
NICHHD, Sect Tissue Biophys & Biomimet, Lab Integrated Med Biophys, Natl Inst Hlth, Bethesda, MD 20892 USATel Aviv Univ, George S Wise Fac Life Sci, Dept Neurobiol, IL-69978 Tel Aviv, Israel
机构:
Tel Aviv Univ, Dept Neurobiol, George S Wise Fac Life Sci, IL-69978 Tel Aviv, IsraelTel Aviv Univ, Dept Neurobiol, George S Wise Fac Life Sci, IL-69978 Tel Aviv, Israel
Barazany, Daniel
Assaf, Yaniv
论文数: 0引用数: 0
h-index: 0
机构:
Tel Aviv Univ, Dept Neurobiol, George S Wise Fac Life Sci, IL-69978 Tel Aviv, IsraelTel Aviv Univ, Dept Neurobiol, George S Wise Fac Life Sci, IL-69978 Tel Aviv, Israel
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Bilgic, Berkin
Pfefferbaum, Adolf
论文数: 0引用数: 0
h-index: 0
机构:
Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford, CA 94305 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Pfefferbaum, Adolf
Rohlfing, Torsten
论文数: 0引用数: 0
h-index: 0
机构:MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Rohlfing, Torsten
Sullivan, Edith V.
论文数: 0引用数: 0
h-index: 0
机构:
Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford, CA 94305 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Sullivan, Edith V.
Adalsteinsson, Elfar
论文数: 0引用数: 0
h-index: 0
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA