Dirhodium(II) Carboxylate Catalyzed Formation of 1,2,3-Trisubstituted Indoles from Styryl Azides

被引：62
作者：
Jones, Crystalann [1 ]
Quyen Nguyen [1 ]
Driver, Tom G. [1 ]
机构：
[1] Univ Illinois, Dept Chem, Chicago, IL 60607 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2014年 / 53卷 / 03期
基金：
美国国家卫生研究院;
关键词：
azides; electrocyclic reactions; indole; rhodium; synthetic methods; C-H AMINATION; BOND AMINATION; ARYL AZIDES; PHOTO-ISOMERIZATION; IMIDO COMPLEXES; AROMATIC-AMINES; ONE-POT; CONVERSION; ALKALOIDS; 2-ALKYLIDENECYCLOPENTANONES;
D O I：
10.1002/anie.201308611
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Dirhodium(II)-carboxylate complexes were discovered to promote the selective migration of acyl groups in trisubstituted styryl azides to form 1,2,3-trisubstituted indoles. The styryl azides are readily available in three steps from cyclobutanone and 2-iodoaniline.
引用
收藏
页码：785 / 788
页数：4
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