7-epicylindrospermopsin, a toxic minor metabolite of the cyanobacterium Aphanizomenon ovalisporum from Lake Kinneret, Israel
被引:117
作者:
Banker, R
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机构:Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel
Banker, R
Teltsch, B
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机构:Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel
Teltsch, B
Sukenik, A
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机构:Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel
Sukenik, A
Carmeli, S
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Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, IsraelTel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel
Carmeli, S
[1
]
机构:
[1] Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel
[2] Mekorot Water Co, Cent Lab, IL-17105 Nazareth Illit, Israel
[3] Israel Oceanog & Limnol Res, Kinneret Limnol Lab, IL-14102 Tiberias, Israel
来源:
JOURNAL OF NATURAL PRODUCTS
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2000年
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63卷
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03期
关键词:
D O I:
10.1021/np990498m
中图分类号:
Q94 [植物学];
学科分类号:
071001 ;
摘要:
A toxic minor metabolite, 7-epicylindrospermopsin (1), was isolated from a culture of the cyanobacterium Aphanizomenon ovalisporum isolated from Lake Kinneret in Israel. Homonuclear and inverse-heteronuclear 2D NMR techniques, as well as HRMS and comparison of the NMR data with model compounds, enabled the structure determination of the new compound. Four polymethoxy-1-alkenes, 3-6, were isolated from the lipophilic extract of the cyanobacterium as well.