Ultrasound irradiation enhances the mass transfer and reaction rate in scavenging, avoiding the trouble of time-consuming purification procedure in solution-phase parallel synthesis. An application of this technique is demonstrated in the scavenging of excess isothiocyanates from reaction mixtures.
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F Hoffmann La Roche & Co Ltd, Pharmaceut Res Basel, Discovery Chem, Lead Generat, CH-4070 Basel, SwitzerlandF Hoffmann La Roche & Co Ltd, Pharmaceut Res Basel, Discovery Chem, Lead Generat, CH-4070 Basel, Switzerland
Brodbeck, B
Püllmann, B
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F Hoffmann La Roche & Co Ltd, Pharmaceut Res Basel, Discovery Chem, Lead Generat, CH-4070 Basel, SwitzerlandF Hoffmann La Roche & Co Ltd, Pharmaceut Res Basel, Discovery Chem, Lead Generat, CH-4070 Basel, Switzerland
Püllmann, B
Schmitt, S
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F Hoffmann La Roche & Co Ltd, Pharmaceut Res Basel, Discovery Chem, Lead Generat, CH-4070 Basel, SwitzerlandF Hoffmann La Roche & Co Ltd, Pharmaceut Res Basel, Discovery Chem, Lead Generat, CH-4070 Basel, Switzerland
Schmitt, S
Nettekoven, M
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F Hoffmann La Roche & Co Ltd, Pharmaceut Res Basel, Discovery Chem, Lead Generat, CH-4070 Basel, SwitzerlandF Hoffmann La Roche & Co Ltd, Pharmaceut Res Basel, Discovery Chem, Lead Generat, CH-4070 Basel, Switzerland