Light field otoscope design for 3D in vivo imaging of the middle ear

被引：44

作者：

Bedard, Noah ^{[1
]}

Shope, Timothy ^{[2
]}

Hoberman, Alejandro ^{[2
]}

Haralam, Mary Ann ^{[2
]}

Shaikh, Nader ^{[2
]}

Kovacevic, Jelena ^{[3
]}

Balram, Nikhil ^{[1
]}

Tosic, Ivana ^{[1
]}

机构：

[1] Ricoh Innovat Corp, Cupertino, CA 95014 USA

[2] Univ Pittsburgh, Med Ctr, Childrens Hosp Pittsburgh, Pittsburgh, PA 15213 USA

[3] Carnegie Mellon Univ, Dept Elect & Comp Engn, Pittsburgh, PA 15213 USA

来源：

BIOMEDICAL OPTICS EXPRESS | 2017年 / 8卷 / 01期

关键词：

BIOFILM;

D O I：

10.1364/BOE.8.000260

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We present a light field digital otoscope designed to measure three-dimensional shape of the tympanic membrane. This paper describes the optical and anatomical considerations we used to develop the prototype, along with the simulation and experimental measurements of vignetting, field curvature, and lateral resolution. Using an experimental evaluation procedure, we have determined depth accuracy and depth precision of our system to be 0.05-0.07 mm and 0.21-0.44 mm, respectively. To demonstrate the application of our light field otoscope, we present the first three-dimensional reconstructions of tympanic membranes in normal and otitis media conditions, acquired from children who participated in a feasibility study at the Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center. (C) 2016 Optical Society of America

引用

页码：260 / 272

页数：13

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