Recent advances in CE mediated microanalysis for enzymatic and derivatization reactions

被引:17
作者
Ramana, Pranov [1 ]
Adams, Erwin [1 ]
Augustijns, Patrick [2 ]
Van Schepdael, Ann [1 ]
机构
[1] Univ Leuven, KU Leuven, Dept Pharmaceut & Pharmacol Sci Pharmaceut Anal, Leuven, Belgium
[2] Univ Leuven, KU Leuven, Dept Pharmaceut & Pharmacol Sci Drug Delivery & D, Leuven, Belgium
关键词
CE; Derivatization; Electrophoretically mediated microanalysis; Immobilized enzyme reactors; Transverse diffusion of laminar flow profiles; LAMINAR-FLOW PROFILES; CAPILLARY-ELECTROPHORESIS; TRANSVERSE DIFFUSION; DRUG-METABOLISM; IN-LINE; REACTOR; PRECONCENTRATION; MICROREACTOR; SENSITIVITY; INHIBITORS;
D O I
10.1002/elps.201500300
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This review gives an overview of the applications and recent advances in CE mediated microanalysis. As a continuation of earlier reviews, it covers articles published from a period of mid 2013-early 2015. The article contains three main parts. In the first part of the article, different kinds of in-line CE mediated microanalysis are briefly discussed along with relevant papers regarding in-line CE for enzyme analysis. Recent advances in on-capillary derivatization reactions and immobilized enzyme reactors (IMERs) have been summarized along with their purpose and relevance in the second and third part of the paper, respectively.
引用
收藏
页码:56 / 65
页数:10
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