Lipase catalyzed synthesis of benzyl acetate in solvent-free medium using vinyl acetate as acyl donor

被引：23

作者：

Majumder, Abir B. ^{[1
]}

Singh, Bhupender ^{[1
]}

Dutta, Debjit ^{[1
]}

Sadhukhan, Sushabhan ^{[1
]}

Gupta, Munishwar N. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, New Delhi 110016, India

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2006年 / 16卷 / 15期

关键词：

benzyl acetate; Mucor miehei lipase; lipozyme RM-IM; solvent-free media; low water system;

D O I：

10.1016/j.bmcl.2006.05.006

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Use of vinyl acetate as acyl donor in transesterification of benzyl alcohol catalyzed by a commercially available lipase (Lipozyme (R) RM IM) gave 100% conversion in 10 min. The excess acyl donor and the enzyme could be recovered and reused. Unlike the chemical catalytic processes, it produced no undesirable side product. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：4041 / 4044

页数：4

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