Changes in the Content of Protein and Lipid Oxidative Modification Products in Tumor Tissue at Different Stages of Lung Cancer

被引：1

作者：

Belonogov, R. N. ^{[1
]}

Titova, N. M. ^{[1
]}

Lapeshin, P. V. ^{[2
]}

Ivanova, Yu. R. ^{[1
]}

Shevtsova, A. O. ^{[1
]}

Pokrovskii, A. A. ^{[1
]}

机构：

[1] Siberian Fed Univ, Dept Physicochem Biol, Novosibirsk, Russia

[2] Krasnoyarsk State Med Univ, Dept Radiotherapy & Oncol, Krasnoyarsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2009年 / 147卷 / 05期

关键词：

oxidative modification of proteins; lipid peroxidation; lung cancer;

D O I：

10.1007/s10517-009-0565-4

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The content of LPO products ( conjugated dienes, MDA) and products of oxidative modification of proteins ( protein carbonyl derivatives) is reduced in tumor tissue in comparison with normal tissue and varies depending on the disease stage.

引用

页码：630 / 631

页数：2

共 11 条

[1]

ANOTONEEVA II, 2007, KLIN GERONTOL, P7

[2]

BOLDYREV AA, 2001, SOROS OBRAZ ZH, V7, P21

[3] Lipid peroxidation and renal cell carcinoma: Further supportive evidence and new mechanistic insights [J].

Gago-Dominguez, M ;

Castelao, JE .

FREE RADICAL BIOLOGY AND MEDICINE, 2006, 40 (04) :721-733

[4]

KAGAN VE, 1986, BIOPHYSICS PROGR SCI, V18

[5] Antioxidant enzymes and redox regulating thiol proteins in malignancies of human lung [J].

Kinnula, VL ;

Pääkkö, P ;

Soini, Y .

FEBS LETTERS, 2004, 569 (1-3) :1-6

[6]

LEVINE RL, 1994, METHOD ENZYMOL, V233, P346

[7] Inflammation, a key event in cancer development [J].

Lu, HT ;

Ouyang, WM ;

Huang, CS .

MOLECULAR CANCER RESEARCH, 2006, 4 (04) :221-233

[8]

Men'shchikova E. B., 2008, OXIDATIVE STRESS PAT

[9]

SKULACHEV VP, 2001, SOROS OBRAZOVAT ZH, V7, P4

[10]

Stalnaya I.D., 1977, SOVREMENNYE METODY B, P66

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