Beta-blockers in the environment: Part II. Ecotoxicity study

被引：101

作者：

Maszkowska, Joanna ^{[1
]}

Stolte, Stefan ^{[1
,2
]}

Kumirska, Jolanta ^{[1
]}

Lukaszewicz, Paulina ^{[1
]}

Mioduszewska, Katarzyna ^{[1
]}

Puckowski, Alan ^{[1
]}

Caban, Magda ^{[1
]}

Wagil, Marta ^{[1
]}

Stepnowski, Piotr ^{[1
]}

Bialk-Bielinska, Anna ^{[1
,2
]}

机构：

[1] Univ Gdansk, Inst Environm & Human Hlth Protect, Dept Environm Anal, Fac Chem, PL-80308 Gdansk, Poland

[2] Univ Bremen, UFT Ctr Environm Res & Sustainable Technol, D-28359 Bremen, Germany

来源：

SCIENCE OF THE TOTAL ENVIRONMENT | 2014年 / 493卷

关键词：

Green algae; Duckweed; Soil and marine bacteria; RECEPTOR-BLOCKING PHARMACEUTICALS; JOINT ALGAL TOXICITY; RISK-ASSESSMENT; DAPHNIA-MAGNA; LEMNA-MINOR; CHEMICALS; MIXTURES; PROPRANOLOL; RECOVERY; WATERS;

D O I：

10.1016/j.scitotenv.2014.06.039

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The increasing consumption of beta-blockers (BB) has caused their presence in the environment to become more noticeable. Even though BB are safe for human and veterinary usage, ecosystems may be exposed to these substances. In this study, three selected BB: propranolol, metoprolol and nadolol were subjected to ecotoxicity study. Ecotoxicity evaluation was based on a flexible ecotoxicological test battery including organisms, representing different trophic levels and complexity: marine bacteria (Vibrio fischeri), soil/sediment bacteria (Arthrobacter globiformis), green algae (Scenedesmus vacuolatus) and duckweed (Lemna minor). All the ecotoxicological studies were supported by instrumental analysis to measure deviation between nominal and real test concentrations. Based on toxicological data from the green algae test (S. vacuolatus) propranolol and metoprolol can be considered to be harmful to aquatic organisms. However, sorption explicitly inhibits the hazardous effects of BB, therefore the risks posed by these compounds for the environment are of minor importance. (c) 2014 Elsevier B.V. All rights reserved.

引用

页码：1122 / 1126

页数：5

共 39 条

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