Bioinspired Modifications of PEEK Implants for Bone Tissue Engineering

被引：53
作者：
Gu, Xinming [1 ]
Sun, Xiaolin [1 ]
Sun, Yue [1 ]
Wang, Jia [1 ]
Liu, Yiping [1 ]
Yu, Kaixuan [1 ]
Wang, Yao [1 ]
Zhou, Yanmin [1 ]
机构：
[1] Jilin Univ, Hosp Stomatol, Dept Oral Implantol, Changchun, Peoples R China
来源：
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY | 2021年 / 8卷
关键词：
polyetheretherketone; surface modification; implants; bioactivity; osseointegration; FIBER-REINFORCED POLYETHERETHERKETONE; POLYETHER-ETHER-KETONE; IN-VIVO EVALUATION; MECHANICAL-PROPERTIES; SURFACE-ENERGY; POROUS POLYETHERETHERKETONE; CELL RESPONSES; ANTIBACTERIAL PROPERTIES; OSTEOBLAST ADHESION; BIOACTIVE COMPOSITE;
D O I：
10.3389/fbioe.2020.631616
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In recent years, polyetheretherketone (PEEK) has been increasingly employed as an implant material in clinical applications. Although PEEK is biocompatible, chemically stable, and radiolucent and has an elastic modulus similar to that of natural bone, it suffers from poor integration with surrounding bone tissue after implantation. To improve the bioactivity of PEEK, numerous strategies for functionalizing the PEEK surface and changing the PEEK structure have been proposed. Inspired by the components, structure, and function of bone tissue, this review discusses strategies to enhance the biocompatibility of PEEK implants and provides direction for fabricating multifunctional implants in the future.
引用
收藏
页数：15
相关论文
共 152 条
[1]  
Ambard Alberto J, 2006, J Prosthodont, V15, P321, DOI 10.1111/j.1532-849X.2006.00129.x
[2]  
[Anonymous], 2010, J ORAL MAXILLOFACIAL, DOI DOI 10.5037/JOMR.2010.1303
[3]  
Anselme K, 2000, J BIOMED MATER RES, V49, P155, DOI 10.1002/(SICI)1097-4636(200002)49:2<155::AID-JBM2>3.0.CO
[4]  
2-J
[5]   The role of cortical bone and its microstructure in bone strength [J].
Augat, Peter ;
Schorlemmer, Sandra .
AGE AND AGEING, 2006, 35 :27-31
[6]   Nano-hydroxyapatite-coated PEEK implants: A pilot study in rabbit bone [J].
Barkarmo, Sargon ;
Wennerberg, Ann ;
Hoffman, Maria ;
Kjellin, Per ;
Breding, Karin ;
Handa, Paul ;
Stenport, Victoria .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2013, 101 (02) :465-471
[7]   Electrophoretic co-deposition of PEEK-hydroxyapatite composite coatings for biomedical applications [J].
Bastan, Fatih E. ;
Rehman, Muhammad Atiq Ur ;
Avcu, Yasemin Yildiran ;
Avcu, Egemen ;
Ustel, Fatih ;
Boccaccin, Aldo R. .
COLLOIDS AND SURFACES B-BIOINTERFACES, 2018, 169 :176-182
[8]   Fabrication and characterization of an electrostatically bonded PEEK- hydroxyapatite composites for biomedical applications [J].
Bastan, Fatih Erdem .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2020, 108 (06) :2513-2527
[9]  
Binyamin Gary, 2006, Semin Pediatr Surg, V15, P276, DOI 10.1053/j.sempedsurg.2006.07.007
[10]   The influence of abutment surface roughness on plaque accumulation and peri-implant mucositis [J].
Bollen, CML ;
Papaioanno, W ;
VanEldere, J ;
Schepers, E ;
Quirynen, M ;
vanSteenberghe, D .
CLINICAL ORAL IMPLANTS RESEARCH, 1996, 7 (03) :201-211
12345678910