Brominated metabolites from an Okinawan Laurencia intricata

被引：35

作者：

Suzuki, M ^{[1
]}

Takahashi, Y

Mitome, Y

Itoh, T

Abe, T

Masuda, M

机构：

[1] Hokkaido Univ, Grad Sch Environm Earth Sci, Div Mat Sci, Sapporo, Hokkaido 0600810, Japan

[2] Hokkaido Univ Museum, Sapporo, Hokkaido 0600810, Japan

[3] Hokkaido Univ, Grad Sch Sci, Div Biol Sci, Sapporo, Hokkaido 0600810, Japan

来源：

PHYTOCHEMISTRY | 2002年 / 60卷 / 08期

关键词：

Laurencia intricata; Rhodomelaceae; red alga; C-15; acetogenin; sesquiterpene; halogenated compound; chemotaxonomy;

D O I：

10.1016/S0031-9422(02)00151-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two halogenated C-15 acetogenins, itomanallenes A and B, with a terminal bromoallene moiety along with a halogenated sesquiterpene, itomanol, have been isolated from the red alga Laurencia intricata collected in Okinawan waters. Their structures were deduced from 1D and 2D NMR experiments including H-1-H-1 COSY, HSQC, HMBC, and NOESY methods. The alcohol corresponding to itomanallene B seems to be a plausible precursor of itomanallene A, which has an unusual 2,10-dioxabicyclo[7.3.0]dodecene skeleton. Itomanol was found to be a selinane-type bromosesquiterpenoid, and is the first example of a selinane to be isolated from Japanese Laurencia species. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：861 / 867

页数：7

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