Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD)

被引:233
作者
Bellentani, Stefano [1 ]
Marino, Mariano [1 ]
机构
[1] Azienda USL Modena, Liver & Nutr Ctr, Ramazzini Hosp Carpi, I-41012 Modena, Italy
关键词
NAFLD; NASH; prevalence; incidence; natural history; epidemiology; GENERAL-POPULATION; RISK-FACTORS; METABOLIC SYNDROME; HEPATIC STEATOSIS; UNITED-STATES; FOLLOW-UP; AMINOTRANSFERASE LEVELS; CRYPTOGENIC CIRRHOSIS; CLINICAL-FEATURES; JAPANESE ADULTS;
D O I
10.1016/S1665-2681(19)31820-4
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The authors summarize and update the most recent knowledge in the field of prevalence, natural history and incidence of Non Alcoholic Fatty Liver Disease (NAFLD) and Non Alcoholic Steatohepatitis (NASH). These novel diseases, firstly recognized at the beginning of the second millennium, arose suddenly to the attention of the clinicians, because they are the hepatic expression of the "so-called" metabolic syndrome. Due to the epidemic burden of obesity, diabetes, and metabolic diseases, NAFLD and NASH will become soon probably the most common hepatic disease worldwide, and they surely will keep busy our future young hepatologists.
引用
收藏
页码:S4 / S8
页数:5
相关论文
共 76 条
  • [1] The natural history of nonalcoholic fatty liver disease: A population-based cohort study
    Adams, LA
    Lymp, JF
    St Sauver, J
    Sanderson, SO
    Lindor, KD
    Feldstein, A
    Angulo, P
    [J]. GASTROENTEROLOGY, 2005, 129 (01) : 113 - 121
  • [2] The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies
    Adams, LA
    Sanderson, S
    Lindor, KD
    Angulo, P
    [J]. JOURNAL OF HEPATOLOGY, 2005, 42 (01) : 132 - 138
  • [3] Nonalcoholic fatty liver disease
    Adams, Leon A.
    Lindor, Keith D.
    [J]. ANNALS OF EPIDEMIOLOGY, 2007, 17 (11) : 863 - 869
  • [4] Non-alcoholic fatty liver disease
    Alba, LM
    Lindor, K
    [J]. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2003, 17 (08) : 977 - 986
  • [5] GI Epidemiology: nonalcoholic fatty liver disease
    Angulo, P.
    [J]. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2007, 25 (08) : 883 - 889
  • [6] Nonalcoholic fatty liver disease
    Brunt, Elizabeth M.
    Wong, Vincent W. -S.
    Nobili, Valerio
    Day, Christopher P.
    Sookoian, Silvia
    Maher, Jacquelyn J.
    Bugianesi, Elisabetta
    Sirlin, Claude B.
    Neuschwander-Tetri, BrentA.
    Rinella, Mary E.
    [J]. NATURE REVIEWS DISEASE PRIMERS, 2015, 1
  • [7] Angulo Paul, 2005, Rev Gastroenterol Mex, V70 Suppl 3, P52
  • [8] Araújo LMB, 1998, DIABETES METAB, V24, P458
  • [9] NONALCOHOLIC STEATOHEPATITIS - AN EXPANDED CLINICAL ENTITY
    BACON, BR
    FARAHVASH, MJ
    JANNEY, CG
    NEUSCHWANDERTETRI, BA
    [J]. GASTROENTEROLOGY, 1994, 107 (04) : 1103 - 1109
  • [10] Prevalence of and risk factors for nonalcoholic fatty liver disease: The Dionysos Nutrition and Liver Study
    Bedogni, G
    Miglioli, L
    Masutti, F
    Tiribelli, C
    Marchesini, G
    Bellentani, S
    [J]. HEPATOLOGY, 2005, 42 (01) : 44 - 52