Bell's palsy in children: Current treatment patterns in Australia and New Zealand. A PREDICT study

被引：9

作者：

Babl, Franz E. ^{[1
,2
,3
]}

Gardiner, Kaya K. ^{[2
]}

Kochar, Amit ^{[6
]}

Wilson, Catherine L. ^{[2
]}

George, Shane A. ^{[7
]}

Zhang, Michael ^{[11
]}

Furyk, Jeremy ^{[8
,9
]}

Thosar, Deepali ^{[12
]}

Cheek, John A. ^{[1
,2
,4
]}

Krieser, David ^{[5
]}

Rao, Arjun S. ^{[13
]}

Borland, Meredith L. ^{[14
,15
,16
]}

Cheng, Nicholas ^{[12
]}

Phillips, Natalie T. ^{[10
]}

Sinn, Kam K. ^{[17
]}

Neutze, Jocelyn M. ^{[18
,19
]}

Dalziel, Stuart R. ^{[19
,20
]}

机构：

[1] Royal Childrens Hosp, Emergency Dept, Melbourne, Vic, Australia

[2] Murdoch Childrens Res Inst, Clin Sci Theme, Melbourne, Vic, Australia

[3] Univ Melbourne, Dept Paediat, Fac Med Dent & Hlth Sci, Melbourne, Vic, Australia

[4] Monash Med Ctr, Emergency Dept, Melbourne, Vic, Australia

[5] Sunshine Hosp, Emergency Dept, Melbourne, Vic, Australia

[6] Womens & Childrens Hosp, Emergency Dept, Adelaide, SA, Australia

[7] Griffith Univ, Sch Med, Gold Coast Univ Hosp, Emergency Dept, Gold Coast, Australia

[8] Townsville Hosp, Emergency Dept, Townsville, Qld, Australia

[9] James Cook Univ, Coll Med & Dent, Townsville, Qld, Australia

[10] Lady Cilento Childrens Hosp, Emergency Dept, Brisbane, Qld, Australia

[11] John Hunter Hosp, Emergency Dept, Newcastle, NSW, Australia

[12] Childrens Hosp, Emergency Dept, Westmead, NSW, Australia

[13] Sydney Childrens Hosp, Emergency Dept, Sydney, NSW, Australia

[14] Univ Western Australia, Princess Margaret Hosp Children, Emergency Dept, Perth, WA, Australia

[15] Univ Western Australia, Sch Paediat & Child Hlth, Perth, WA, Australia

[16] Univ Western Australia, Sch Primary Aboriginal & Rural Hlth Care, Perth, WA, Australia

[17] Canberra Hosp, Emergency Dept, Canberra, ACT, Australia

[18] KidzFirst Middlemore Hosp, Emergency Dept, Auckland, New Zealand

[19] Univ Auckland, Liggins Inst, Auckland, New Zealand

[20] Starship Childrens Hosp, Emergency Dept, Auckland, New Zealand

来源：

JOURNAL OF PAEDIATRICS AND CHILD HEALTH | 2017年 / 53卷 / 04期

基金：

英国医学研究理事会;

关键词：

Bell's palsy; child; facial palsy; prednisolone; NEUROMYELITIS-OPTICA; PREDNISOLONE;

D O I：

10.1111/jpc.13463

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

AimThe aetiology and clinical course of Bell's palsy may be different in paediatric and adult patients. There is no randomised placebo controlled trial (RCT) to show effectiveness of prednisolone for Bell's palsy in children. The aim of the study was to assess current practice in paediatric Bell's palsy in Australia and New Zealand Emergency Departments (ED) and determine the feasibility of conducting a multicentre RCT within the Paediatric Research in Emergency Departments International Collaborative (PREDICT). MethodsA retrospective analysis of ED medical records of children less than 18 years diagnosed with Bell's palsy between 1 January, 2012 and 31 December, 2013 was performed. Potential participants were identified from ED information systems using Bell's palsy related search terms. Repeat presentations during the same illness were excluded but relapses were not. Data on presentation, diagnosis and management were entered into an online data base (REDCap). ResultsThree hundred and twenty-three presentations were included from 14 PREDICT sites. Mean age at presentation was 9.0 (SD 5.0) years with 184 (57.0%) females. Most (238, 73.7%) presented to ED within 72 h of symptoms, 168 (52.0%) had seen a doctor prior. In ED, 218 (67.5%) were treated with steroids. Prednisolone was usually prescribed for 9 days at around 1 mg/kg/day, with tapering in 35.7%. ConclusionTreatment of Bell's palsy in children presenting to Australasian EDs is varied. Prednisolone is commonly used in Australasian EDs, despite lack of high-level paediatric evidence. The study findings confirm the feasibility of an RCT of prednisolone for Bell's palsy in children.

引用

页码：339 / 342

页数：4

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