Scabies

被引:90
作者
Hicks, Maria I. [1 ]
Elston, Dirk M. [1 ]
机构
[1] Geisinger Dermatol, Danville, PA 17822 USA
关键词
ivermectin; permethrin; scabies; LANGERHANS CELL HISTIOCYTOSIS; BENZYL BENZOATE LOTION; SARCOPTES-SCABIEI; NORWEGIAN SCABIES; ORAL IVERMECTIN; CRUSTED SCABIES; BULLOUS SCABIES; CHILDHOOD SCABIES; PERMETHRIN CREAM; LINDANE LOTION;
D O I
10.1111/j.1529-8019.2009.01243.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Scabies is an ectoparasite caused by the mite Sarcoptes scabiei var hominis, an obligate human parasite. There are about 300 million cases of scabies in the world each year. Common predisposing factors are overcrowding, immigration, poor hygiene, poor nutritional status, homelessness, dementia, and sexual contact. Direct skin-to-skin contact between 15 and 20 minutes is needed to transfer the mites from one person to another. The diagnosis suspected with a clinical history of itch, worse at night, affecting other family members, clinical distribution, and appearance. Definite diagnosis relies on microscopic identification of the mites, eggs, or fecal pellets with 10% potassium hydroxide, ink enhancement, tetracycline fluorescence tests, or mineral oil; other methods include: epiluminescence light microscopy and S. scabiei DNA. The most commonly used treatment modalities are permethrin and ivermectin. Persistence of symptoms for 2-6 weeks after successful treatment is common. Most recurrences are because of reinfection from untreated contacts.
引用
收藏
页码:279 / 292
页数:14
相关论文
共 121 条
[1]  
ALLMERICA F, 2000, BRIT J DERMATOL, V142, P969
[2]   Lesson of the week - Norwegian scabies misdiagnosed as an adverse drug reaction [J].
Almond, DS ;
Green, CJ ;
Geurin, DM ;
Evans, S .
BRITISH MEDICAL JOURNAL, 2000, 320 (7226) :35-36
[3]   Ivermectin for scabies [J].
Altman, JS .
ARCHIVES OF DERMATOLOGY, 1999, 135 (12) :1550-1550
[4]   Outbreak of scabies in Norwegian nursing homes and home care patients: control and prevention [J].
Andersen, BM ;
Haugen, H ;
Rasch, M ;
Haugen, AH ;
Tageson, A .
JOURNAL OF HOSPITAL INFECTION, 2000, 45 (02) :160-164
[5]  
Angeles RM, 2005, ARCH PATHOL LAB MED, V129, P810
[6]  
[Anonymous], 2007, COCHRANE DATABASE SY
[7]  
Ansarin Habib, 2006, Dermatol Online J, V12, P19
[8]   Modulation of cytokine expression in human keratinocytes and fibroblasts by extracts of scabies mites [J].
Arlian, LG ;
Morgan, MS ;
Neal, JS .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2003, 69 (06) :652-656
[9]   SARCOPTES-SCABIEI - HISTOPATHOLOGICAL CHANGES ASSOCIATED WITH ACQUISITION AND EXPRESSION OF HOST IMMUNITY TO SCABIES [J].
ARLIAN, LG ;
RAPP, CM ;
VYSZENSKIMOHER, DL ;
MORGAN, MS .
EXPERIMENTAL PARASITOLOGY, 1994, 78 (01) :51-63
[10]   SARCOPTES-SCABIEI - THE CIRCULATING ANTIBODY-RESPONSE AND INDUCED IMMUNITY TO SCABIES [J].
ARLIAN, LG ;
MORGAN, MS ;
VYSZENSKIMOHER, DL ;
STEMMER, BL .
EXPERIMENTAL PARASITOLOGY, 1994, 78 (01) :37-50