Urine-based assays for the detection of bladder cancer

被引：32

作者：

Villicana, Patrick ^{[1
]}

Whiting, Bryant ^{[1
]}

Goodison, Steve ^{[2
]}

Rosser, Charles J. ^{[1
]}

机构：

[1] Univ Florida, Coll Med, Dept Urol, Gainesville, FL 32610 USA

[2] Univ Florida, Dept Surg, Jacksonville, FL 32209 USA

来源：

BIOMARKERS IN MEDICINE | 2009年 / 3卷 / 03期

关键词：

bladder cancer; genomics; marker; NMP; 22; proteomics; urinary cytology; urine; IN-SITU HYBRIDIZATION; TRANSITIONAL-CELL CARCINOMA; CARE PROTEOMIC ASSAY; BTA STAT TEST; GENE-EXPRESSION; TUMOR-MARKERS; UROTHELIAL CARCINOMA; PROSTATE-CANCER; HYALURONIC-ACID; FOLLOW-UP;

D O I：

10.2217/BMM.09.23

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Bladder cancer is one of the most prevalent cancers worldwide. Furthermore, nonmuscle invasive bladder cancer has a 70% rate of recurrence, making it a considerable strain to the healthcare system. Patients with bladder cancer require repeat cystoscopic examinations of the bladder to monitor for tumor recurrence. The reason these patients have to undergo these costly, painful, invasive procedures is owing to the absence of accurate urine-based assays to detect the presence of bladder cancer noninvasively. Consequently, the development of a urine-based test to detect bladder cancer would be of tremendous benefit to both patients and healthcare systems. This article reports some of the more prominent urine markers in use today, In addition, the article will highlight some new technologies that are used to investigate novel urinary markers.

引用

页码：265 / 274

页数：10

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