Prevention of Recurrent Urinary Tract Infections in Women Antimicrobial and Nonantimicrobial Strategies

被引：33

作者：

Geerlings, Suzanne E. ^{[1
]}

Beerepoot, Marielle A. J. ^{[1
]}

Prins, Jan M. ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Internal Med, Div Infect Dis, NL-1105 AZ Amsterdam, Netherlands

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2014年 / 28卷 / 01期

关键词：

Recurrent urinary tract infections; Antimicrobial prophylaxis; Non-antimicrobial strategies; Cranberries; Lactobacilli; Methenamine; VAGINAL MUCOSAL VACCINE; DOUBLE-BLIND; ESCHERICHIA-COLI; POSTMENOPAUSAL WOMEN; PROPHYLACTIC AGENT; CONTROLLED-TRIAL; PARALLEL-GROUP; ASCORBIC-ACID; LONG-TERM; CRANBERRY;

D O I：

10.1016/j.idc.2013.10.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recurrent urinary tract infections (UTIs) are common, especially in women. Low-dose daily or postcoital antimicrobial prophylaxis is effective for prevention of recurrent UTIs and women can self-diagnose and self-treat a new UTI with antibiotics. The increasing resistance rates of Escherichia coli to antimicrobial agents has, however, stimulated interest in nonantibiotic methods for the prevention of UTIs. This article reviews the literature on efficacy of different forms of nonantibiotic prophylaxis. Future studies with lactobacilli strains (oral and vaginal) and the oral immunostimulant OM-89 are warranted.

引用

页码：135 / +

页数：14

共 38 条

[31] Randomized, Placebo-Controlled Phase 2 Trial of a Lactobacillus crispatus Probiotic Given Intravaginally for Prevention of Recurrent Urinary Tract Infection [J].