Vilsmeier-Haack reactions of carbonyl compounds: synthesis of substituted pyrones and pyridines

被引：40

作者：

Thomas, AD ^{[1
]}

Josemin ^{[1
]}

Asokan, CV ^{[1
]}

机构：

[1] Mahatma Gandhi Univ, Sch Chem Sci, Kottayam 686560, India

来源：

TETRAHEDRON | 2004年 / 60卷 / 23期

关键词：

D O I：

10.1016/j.tet.2004.04.017

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Vilsmeier-Haack reaction of substituted phenylacetones leads to the formation of conjugated iminium salts which on aqueous basic work up afford 3-formyl-4-pyrones and on ammonium acetate-induced cyclization afford 5-aryl-4-chloronicotinaldehydes in good yields. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：5069 / 5076

页数：8

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