Structure of constituents isolated from the flower buds of Cananga odorata and their inhibitory effects on aldose reductase

被引：12

作者：

Matsumoto, Takahiro ^{[1
]}

Nakamura, Seikou ^{[1
]}

Fujimoto, Katsuyoshi ^{[1
]}

Ohta, Tomoe ^{[1
]}

Ogawa, Keiko ^{[1
]}

Yoshikawa, Masayuki ^{[1
]}

Matsuda, Hisashi ^{[1
]}

机构：

[1] Kyoto Pharmaceut Univ, Dept Pharmacognosy, Yamashina Ku, Kyoto 6078412, Japan

来源：

JOURNAL OF NATURAL MEDICINES | 2014年 / 68卷 / 04期

基金：

日本学术振兴会;

关键词：

Cananga odorata; Canangaterpene; Aldose reductase; Medicinal flower; CHINESE CAMELLIA-JAPONICA; ACYLATED SUCROSES; OLEANANE-TYPE; PRUNUS-MUME; TRITERPENE SAPONINS; MELANOGENESIS; TERPENOIDS; GLYCOSIDES; LEAVES;

D O I：

10.1007/s11418-014-0843-y

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three new terpenoid derivatives, canangaterpenes IV-VI, were isolated from the flower buds of Cananga odorata, cultivated in Thailand, together with eight known flavonoids. The chemical structures of the new compounds were elucidated on the basis of chemical and physicochemical evidence. The inhibitory effects of the isolated compounds on aldose reductase were also investigated. Several terpenoid derivatives and flavonoids were shown to inhibit aldose reductase.

引用

收藏

页码：709 / 716

页数：8

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