Advances in nanomedicines for malaria treatment

被引:71
作者
Aditya, N. P. [1 ]
Vathsala, P. G. [2 ]
Vieira, V. [3 ]
Murthy, R. S. R. [4 ]
Souto, E. B. [3 ]
机构
[1] Sejong Univ, Dept Food Sci & Technol, Food Nanotechnol Lab, Seoul 143747, South Korea
[2] Indian Inst Sci, Dept Biochem, Bangalore 560012, Karnataka, India
[3] Fernando Pessoa Univ, Fac Hlth Sci, P-4200150 Oporto, Portugal
[4] ISF Coll Pharm, Ctr Nanomed, Moga, Punjab, India
关键词
Malaria; Plasmodium; Nanomedicine; Colloidal carriers; Toxicity; Microfluidics; Lipids; Polymers; Solid lipid nanoparticles; Liposomes; Dendrimers; PLASMODIUM-VIVAX MALARIA; SOLID LIPID NANOPARTICLES; SEVERE FALCIPARUM-MALARIA; PRIME-BOOST IMMUNIZATION; RED-BLOOD-CELLS; ANOPHELES-CULICIFACIES COMPLEX; ANTIBODY-BEARING LIPOSOMES; IN-VITRO; ANTIMALARIAL-DRUGS; INFECTED ERYTHROCYTES;
D O I
10.1016/j.cis.2013.10.014
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Malaria is an infectious disease that mainly affects children and pregnant women from tropical countries. The mortality rate of people infected with malaria per year is enormous and became a public health concern. The main factor that has contributed to the success of malaria proliferation is the increased number of drug resistant parasites. To counteract this trend, research has been done in nanotechnology and nanomedicine, for the development of new biocompatible systems capable of incorporating drugs, lowering the resistance progress, contributing for diagnosis, control and treatment of malaria by target delivery. In this review, we discussed the main problems associated with the spread of malaria and the most recent developments in nanomedicine for anti-malarial drug delivery. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:1 / 17
页数:17
相关论文
共 206 条
[1]   Curcuminoids-loaded liposomes in combination with arteether protects against Plasmodium berghei infection in mice [J].
Aditya, N. P. ;
Chimote, Geetanjali ;
Gunalan, Karthigayan ;
Banerjee, Rinti ;
Patankar, Swati ;
Madhusudhan, Basavaraj .
EXPERIMENTAL PARASITOLOGY, 2012, 131 (03) :292-299
[2]   Arthemeter-loaded lipid nanoparticles produced by modified thin-film hydration: Pharmacokinetics, toxicological and in vivo anti-malarial activity [J].
Aditya, N. P. ;
Patankar, S. ;
Madhusudhan, B. ;
Murthy, R. S. R. ;
Souto, E. B. .
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2010, 40 (05) :448-455
[3]   FUNCTIONAL-DRUG TARGETING TO ERYTHROCYTES INVIVO USING ANTIBODY BEARING LIPOSOMES AS DRUG VEHICLES [J].
AGRAWAL, AK ;
SINGHAL, A ;
GUPTA, CM .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 148 (01) :357-361
[4]   Oral delivery of curcumin bound to chitosan nanoparticles cured Plasmodium yoelii infected mice [J].
Akhtar, Feroz ;
Rizvi, M. Moshahid Alam ;
Kar, Santosh Kumar .
BIOTECHNOLOGY ADVANCES, 2012, 30 (01) :310-320
[5]   Selective Sweeps and Genetic Lineages of Plasmodium falciparum Drug -Resistant Alleles in Ghana [J].
Alam, Md Tauqeer ;
de Souza, Dziedzom K. ;
Vinayak, Sumiti ;
Griffing, Sean M. ;
Poe, Amanda C. ;
Duah, Nancy O. ;
Ghansah, Anita ;
Asamoa, Kwame ;
Slutsker, Laurence ;
Wilson, Michael D. ;
Barnwell, John W. ;
Udhayakumar, Venkatachalam ;
Koram, Kwadwo A. .
JOURNAL OF INFECTIOUS DISEASES, 2011, 203 (02) :220-227
[6]   Evaluation of liposomal formulations containing the antimalarial agent, arteether [J].
AlAngary, AA ;
AlMeshal, MA ;
Bayomi, MA ;
Khidr, SH .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1996, 128 (1-2) :163-168
[7]  
Alkhunaizi AM, 2008, SAUDI MED J, V29, P293
[8]   Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children:: single-blind extended follow-up of a randomised controlled trial [J].
Alonso, PL ;
Sacarlal, J ;
Aponte, JJ ;
Leach, A ;
Macete, E ;
Aide, P ;
Sigauque, B ;
Milman, J ;
Mandomando, I ;
Bassat, Q ;
Guinovart, C ;
Espasa, M ;
Corachan, S ;
Lievens, M ;
Navia, MM ;
Dubois, MC ;
Menendez, C ;
Dubovsky, F ;
Cohen, J ;
Thompson, R ;
Ballou, WR .
LANCET, 2005, 366 (9502) :2012-2018
[9]   Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children:: randomised controlled trial [J].
Alonso, PL ;
Sacarlal, J ;
Aponte, JJ ;
Leach, A ;
Macete, E ;
Milman, J ;
Mandomando, I ;
Spiessens, B ;
Guinovart, C ;
Espasa, M ;
Bassat, Q ;
Aide, P ;
Ofori-Anyinam, O ;
Navia, MM ;
Corachan, S ;
Ceuppens, M ;
Dubois, MC ;
Demoitié, MA ;
Dubovsky, F ;
Menéndez, C ;
Tornieporth, N ;
Ballou, WR ;
Thompson, R ;
Cohen, J .
LANCET, 2004, 364 (9443) :1411-1420
[10]   Quality of essential drugs in tropical countries: evaluation of antimalarial drugs in the Brazilian Health System [J].
Andrade Nogueira, Fernando Henrique ;
Moreira-Campos, Ligia Maria ;
dos Santos, Roseli La Corte ;
Pianetti, Gerson Antonio .
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 2011, 44 (05) :582-586