Elastic intramedullary nailing of the femur fracture in patients affected by osteogenesis imperfecta type 3: Indications, limits and pitfalls

被引:8
作者
Persiani, Pietro [1 ]
Martini, Lorena [1 ]
Ranaldi, Filippo Maria [1 ]
Zambrano, Anna [2 ]
Celli, Mauro [2 ]
Celli, Luca [2 ]
D'Eufemia, Patrizia [2 ]
Villani, Ciro [1 ]
机构
[1] Sapienza Univ Rome, Dept Orthopaed & Traumatol, Policlin Umberto I, Dept Anat Histol Forens Med & Orthopaed Sci, Rome, Italy
[2] Sapienza Univ Rome, Ctr Congenital Osteodystrophies, Paediat Dept, Policlin Umberto I, Rome, Italy
来源
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | 2019年 / 50卷
关键词
Osteogenesis imperfecta; Femural fractures; Elastic nailing; Indications; Limits; Pitfalls; DUVAL TELESCOPIC ROD; TERIPARATIDE TREATMENT; CHILDREN; DEFORMITIES; EXPERIENCE; FORM;
D O I
10.1016/j.injury.2019.01.045
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Introduction: Patients with Osteogenesis Imperfecta (OI) Type 3 may exhibit both primitive deformities and secondary fracture malunions on a femoral level. The orthopaedic surgeon's objective is to cure the deformities in order to prevent fractures and to treat the fractures in order to prevent deformities, by using telescopic nails as the gold standard method of fixation. However, the titanium elastic nail (TEN) is indicated as a possible alternative in certain selected cases. Materials and methods: The Centre for Congenital Osteodystrophy of the Sapienza University of Rome follows 485 patients with osteogenesis imperfecta. For the purpose of this study, we selected 36 patients with OI type 3 (15 females and 21 males), aged between 2 and 10 years old, who were surgically treated for femur fractures with Titanium Elastic Nail (TEN) from January 2007 to December 2009. In 12 cases a single TEN was implanted, while 24 of the cases were treated by implanting 2 TENs with the Sliding Nail (SN) technique. A retrospective evaluation was carried out by analysing the data from the medical charts and dossiers related to pain symptoms, knee and hip Range of Motion (ROM), any possible complications that could cause implant revisions (infections, nail slide failure, nail migration, traumatic events following surgery, delayed consolidation, epiphysiodesis). Results: At the 60th post-surgical month, the revision rate was 75%, mostly due to migration, osteolysis, nail slide failure and nail fracture. The Kaplan-Meier's survival curve analysis showed a coefficient of 0.25-60 months (confidence interval -0.31 and 0.81). Discussion: The percentage of complications and the high rate of revisions recorded in our sample confirm that telescopic nail is the gold standard in the treatment of femoral fractures in patients with OI type 3. Conclusions: In patients under the age of 4, with narrow medullary canals, low life expectancy, few to nil rehabilitative prospectives or severe comorbidities, the use of TEN may be considered as a less invasive approach compared to telescopic nail surgery, however only temporarily, as it will still most probably require a surgical revision a few years down the line. (C) 2019 Elsevier Ltd. All rights reserved.
引用
收藏
页码:S52 / S56
页数:5
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