An Emerging Concept of Lung Adenocarcinoma: What can we learn from EGFR, KRAS, BRAF, HER2 and EML4-ALK gene alterations?

[1] Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (24) : 13790 - 13795

[2] Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways [J]. AMERICAN JOURNAL OF PATHOLOGY, 2003, 163 (05) : 1949 - 1960

[3] Mutational analysis of the HER2 gene in lung tumors from Caucasian patients:: Mutations are mainly present in adenocarcinomas with bronchioloalveolar features [J]. INTERNATIONAL JOURNAL OF CANCER, 2006, 119 (11) : 2586 - 2591

[4] Diversity of gene expression in adenocarcinoma of the lung [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (24) : 13784 - 13789

[5] Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts [J]. JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (31) : 5079 - 5090

[6] EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset [J]. MODERN PATHOLOGY, 2009, 22 (04) : 508 - 515

[7] Identification of bronchioalveolar stem cells in normal lung and lung cancer [J]. CELL, 2005, 121 (06) : 823 - 835

[8] KOBAYASHI T, 1990, CANCER-AM CANCER SOC, V66, P289, DOI 10.1002/1097-0142(19900715)66:2<289::AID-CNCR2820660216>3.0.CO

[9] 2-6

[10] Non-solid oncogenes in solid tumors: EML4-ALK fusion genes in lung cancer [J]. CANCER SCIENCE, 2008, 99 (12) : 2349 - 2355

[1] Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (24) : 13790 - 13795

[2] Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways [J]. AMERICAN JOURNAL OF PATHOLOGY, 2003, 163 (05) : 1949 - 1960

[3] Mutational analysis of the HER2 gene in lung tumors from Caucasian patients:: Mutations are mainly present in adenocarcinomas with bronchioloalveolar features [J]. INTERNATIONAL JOURNAL OF CANCER, 2006, 119 (11) : 2586 - 2591

[4] Diversity of gene expression in adenocarcinoma of the lung [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (24) : 13784 - 13789

[5] Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts [J]. JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (31) : 5079 - 5090

[6] EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset [J]. MODERN PATHOLOGY, 2009, 22 (04) : 508 - 515

[7] Identification of bronchioalveolar stem cells in normal lung and lung cancer [J]. CELL, 2005, 121 (06) : 823 - 835

[8] KOBAYASHI T, 1990, CANCER-AM CANCER SOC, V66, P289, DOI 10.1002/1097-0142(19900715)66:2<289::AID-CNCR2820660216>3.0.CO

[9] 2-6

[10] Non-solid oncogenes in solid tumors: EML4-ALK fusion genes in lung cancer [J]. CANCER SCIENCE, 2008, 99 (12) : 2349 - 2355