Prevalence of Serious Bacterial Infections in Children with Sickle Cell Disease at King Abdulaziz Hospital, Al Ahsa

被引：7

作者：

Alsaif, Manal A. ^{[1
]}

Abdulbaqi, Moshtag ^{[1
]}

Al Noaim, Khalid ^{[2
]}

Aghbari, Mustafa ^{[1
]}

Alabdulqader, Muneera ^{[2
]}

Robinson, Joan L. ^{[3
]}

机构：

[1] King Abdulaziz Hosp, King Abdullah Int Med Res Ctr, Dept Pediat, POB 2477, Al Hasa 31982, Saudi Arabia

[2] King Faisal Univ, Coll Med, Dept Pediat, Al Hasa, Saudi Arabia

[3] Univ Alberta, Dept Pediat, Edmonton, AB, Canada

来源：

MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES | 2021年 / 13卷

关键词：

Serious bacterial infection; Sickle cell disease; Bacteremia; Pneumonia; Osteomyelitis; INVASIVE PNEUMOCOCCAL DISEASE; ACUTE CHEST SYNDROME; OUTPATIENT MANAGEMENT; FEBRILE CHILDREN; PROPHYLAXIS; CEFTRIAXONE; BACTEREMIA; PENICILLIN; FEVER;

D O I：

10.4084/MJHID.2021.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: The main aim was to report the prevalence and severity of serious bacterial infections (SBI) in children with sickle cell disease at King Abdulaziz Hospital (KAH), Al Ahsa, Saudi Arabia, to aid in determining whether outpatient management of such cases is appropriate. Methods: We conducted a retrospective chart review of febrile children less than 14 years of age admitted with sickle cell disease 2005 through 2015. Results: During 320 admissions, 25 children had SBIs (8%) including pneumonia (n=11), osteomyelitis (n=8), bacteremia (n=3, all with Salmonella species) and UTI (n=3). All recovered uneventfully. Conclusion: It appears that in the current era, less than 10% of febrile children with sickle cell disease in our center are diagnosed with an SBI. Over 11 years, there were no sequelae or deaths from SBI. Given these excellent outcomes, outpatient ceftriaxone should be considered for febrile well-appearing children with sickle cell disease if they have no apparent source and parents are judged to be reliable.

引用

页数：7

共 36 条

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