High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline

被引：60
|
作者：
Beteva, A.
Cipriani, F.
Cusack, S.
Delageniere, S.
Gabadinho, J.
Gordon, E. J.
Guijarro, M.
Hall, D. R.
Larsen, S.
Launer, L.
Lavault, C. B.
Leonard, G. A.
Mairs, T.
McCarthy, A.
McCarthy, J.
Meyer, J.
Mitchell, E.
Monaco, S.
Nurizzo, D.
Pernot, P.
Pieritz, R.
Ravelli, R. G. B.
Rey, V.
Shepard, W.
Spruce, D.
Stuart, D. I.
Svensson, O.
Theveneau, P.
Thibault, X.
Turkenburg, J.
Walsh, M.
McSweeney, S. M.
机构：
[1] European Synchrotron Radiat Facil, F-38043 Grenoble, France
[2] European Mol Biol Lab, F-38042 Grenoble, France
[3] MRC, F-38042 Grenoble 9, France
[4] Oxford Prot Prod Facil, Oxford OX3 7BN, England
[5] Well Trust Ctr Human Genet, Div Struct Biol, Oxford OX3 7BN, England
[6] Univ York, Dept Chem, York Struct Biol Lab, York YO10 5DD, N Yorkshire, England
来源：
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY | 2006年 / 62卷
基金：
英国医学研究理事会;
关键词：
D O I：
10.1107/S0907444906032859
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
An automatic data- collection system has been implemented and installed on seven insertion- device beamlines and a bending- magnet beamline at the ESRF ( European Synchrotron Radiation Facility) as part of the SPINE ( Structural Proteomics In Europe) development of an automated structure- determination pipeline. The system allows remote interaction with beamline- control systems and automatic sample mounting, alignment, characterization, data collection and processing. Reports of all actions taken are available for inspection via database modules and web services.
引用
收藏
页码：1162 / 1169
页数：8
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