History of the Discovery of Hepatitis A Virus

被引：17

作者：

Feinstone, Stephen M. ^{[1
]}

机构：

[1] George Washington Univ, Sch Med, Dept Biochem & Mol Med, Washington, DC 20037 USA

来源：

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE | 2019年 / 9卷 / 05期

关键词：

VIRAL-HEPATITIS; TISSUE-CULTURE; FECAL ANTIGEN; MILAN ANTIGEN; CELL-CULTURE; PARTICLES; EPIDEMIC; BLOOD; SERUM; IDENTIFICATION;

D O I：

10.1101/cshperspect.a031740

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Disease outbreaks resembling hepatitis A have been known since antiquity. However, it was not until World War H when two forms of viral hepatitis were clearly differentiated. After the discovery of Australia antigen and its association with hepatitis B, similar methodologies were used to find the hepatitis A virus. The virus was ultimately identified when investigators changed the focus of their search from serum to feces and applied appropriate technology.

引用

页数：14

共 60 条

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