Anxiety and depression in long-term testicular germ cell tumor survivors

被引:35
作者
Vehling, S. [1 ]
Mehnert, A. [1 ,2 ]
Hartmann, M. [3 ]
Oing, C. [4 ]
Bokemeyer, C. [4 ]
Oechsle, K. [4 ]
机构
[1] Univ Med Ctr Hamburg, Dept Med Psychol, D-0246 Hamburg, Germany
[2] Univ Med Ctr Leipzig, Dept Med Psychol & Med Sociol, Div Psychosocial Oncol, Leipzig, Germany
[3] Univ Med Ctr Hamburg, Dept Urol, D-0246 Hamburg, Germany
[4] Univ Med Ctr Hamburg, Dept Oncol Hematol & Bone Marrow Transplantat, Sect Pneumol, D-0246 Hamburg, Germany
关键词
Testicular cancer; Survivorship; Anxiety; Depression; Psychological distress; HEALTH QUESTIONNAIRE PHQ-9; QUALITY-OF-LIFE; CANCER SURVIVORS; GENERAL-POPULATION; FOLLOW-UP; SYMPTOMS; DISORDER; STANDARDIZATION; SUPPORT; GAD-7;
D O I
10.1016/j.genhosppsych.2015.09.001
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: Despite a good prognosis, the typically young age at diagnosis and physical sequelae may cause psychological distress in germ cell tumor survivors. We aimed to determine the frequency of anxiety and depression and analyze the impact of demographic and disease-related factors. Method: We enrolled N=164 testicular germ cell tumor survivors receiving routine follow-up care at the University Cancer Center Hamburg and a specialized private practice (mean, 11.6 years after diagnosis). Patients completed the Generalized Anxiety Disorder Screener-7, the Patient Health Questionnaire-9 and the Memorial Symptom Assessment Scale-Short Form. Results: We found clinically significant anxiety present in 6.1% and depression present in 7.9% of survivors. A higher number of physical symptoms and having children were significantly associated with higher levels of both anxiety and depression in multivariate regression analyses controlling for age at diagnosis, cohabitation, socioeconomic status, time since diagnosis, metastatic disease and relapse. Younger age at diagnosis and shorter time since diagnosis were significantly associated with higher anxiety. Conclusion: Although rates of clinically relevant anxiety and depression were comparably low, attention toward persisting physical symptoms and psychosocial needs related to a young age at diagnosis and having children will contribute to address potential long-term psychological distress in germ cell tumor survivors. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:21 / 25
页数:5
相关论文
共 38 条
[1]  
Aaronson Neil K, 2014, EJC Suppl, V12, P54, DOI 10.1016/j.ejcsup.2014.03.005
[2]   Sexual satisfaction, anxiety, depression and quality of life in testicular cancer survivors [J].
Alacacioglu, Ahmet ;
Ulger, Eda ;
Varol, Umut ;
Yavuzsen, Tugba ;
Akyol, Murat ;
Yildiz, Yasar ;
Yildiz, Ibrahim ;
Bayoglu, Vedat ;
Dirican, Ahmet ;
Demir, Lutfiye ;
Salman, Tarik ;
Kucukzeybek, Yuksel ;
Alacacioglu, Inci ;
Can, Huseyin ;
Tarhan, Mustafa Oktay .
MEDICAL ONCOLOGY, 2014, 31 (07)
[3]  
[Anonymous], 2013, LANCET ONCOL, DOI DOI 10.1016/S1470-2045(13)70244-4
[4]   Testicular cancer survivors' supportive care needs and use of online support: a cross-sectional survey [J].
Bender, Jacqueline L. ;
Wiljer, David ;
To, Matthew J. ;
Bedard, Philippe L. ;
Chung, Peter ;
Jewett, Michael A. S. ;
Matthew, Andrew ;
Moore, Malcolm ;
Warde, Padraig ;
Gospodarowicz, Mary .
SUPPORTIVE CARE IN CANCER, 2012, 20 (11) :2737-2746
[5]   A gerontologic perspective on cancer and aging [J].
Blank, Thomas O. ;
Bellizzi, Keith M. .
CANCER, 2008, 112 (11) :2569-2576
[6]   Health-related quality of life, depression, and sexual function in testicular cancer survivors in a developing country: a Serbian experience [J].
Bumbasirevic, Uros ;
Bojanic, Nebojsa ;
Pekmezovic, Tatjana ;
Janjic, Aleksandar ;
Janicic, Aleksandar ;
Milojevic, Bogomir ;
Tulic, Cane .
SUPPORTIVE CARE IN CANCER, 2013, 21 (03) :757-763
[7]   Identifying psychological morbidity among people with cancer using the Hospital Anxiety and Depression Scale: time to revisit first principles? [J].
Carey, Mariko ;
Noble, Natasha ;
Sanson-Fisher, Robert ;
Mackenzie, Lisa .
PSYCHO-ONCOLOGY, 2012, 21 (03) :229-238
[8]  
Chang VT, 2000, CANCER, V89, P1162, DOI 10.1002/1097-0142(20000901)89:5<1162::AID-CNCR26>3.0.CO
[9]  
2-Y
[10]   Study of anxiety disorder and depression in long-term survivors of testicular cancer [J].
Dahl, AA ;
Haaland, CF ;
Mykletun, A ;
Bremnes, R ;
Dahl, C ;
Klepp, O ;
Wist, E ;
Fosså, SD .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (10) :2389-2395