Structure of poly(lactic-acid) PLA nanofibers scaffolds prepared by electrospinning

被引：45

作者：

Gomez-Pachon, E. Y. ^{[1
]}

Vera-Graziano, R. ^{[2
]}

Montiel Campos, R. ^{[3
]}

机构：

[1] UPTC, Escuela Diseno Ind, Carrera 18 Calle 22, Duitama, Boyaca, Colombia

[2] Univ Nacl Autonoma Mexico, Inst Invest, Mexico City 04510, DF, Mexico

[3] Univ Autonoma Metropolitana Mexico, Dept Polimeros, Mexico City 09340, DF, Mexico

来源：

INTERNATIONAL CONGRESS OF MECHANICAL ENGINEERING AND AGRICULTURAL SCIENCES - CIIMCA 2013 | 2014年 / 59卷

关键词：

MECHANICAL-PROPERTIES; ORIENTATION;

D O I：

10.1088/1757-899X/59/1/012003

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

The structural properties of poly(lactic-acid) PLA nanofiber scaffolds prepared by electrospinning have been correlated with their process condition. The influence of the electrospinning processing parameters on structure including fiber orientation, take-up velocity and post-thermal treatment was analyzed. The structure and the properties of the scaffolds were studied by x-ray diffraction (XRD), atomic force microscope (AFM), scanning electron microscopy (SEM), high resolution transmission electron microscopy (HRTEM), and differential scanning calorimetry (DSC). The existence of crystallinity into the nanofibres of PLA was found. The careful observation by HRTEM shows an amorphous core and a semicrystalline shell structure (supramolecular), and the surface of nanofiber observed by AFM shows a laminate periodic along the main axis of the fiber. These observations will be useful in understanding the structure-property relationships of oriented nanofibre scaffolds for medical or biological applications.

引用

页数：9

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