An Effective Deracemization of trans-1,2-Bis(phenylsulfenyl)cyclohexane

被引：2

作者：

Wojaczynska, Elzbieta ^{[1
]}

Skarzewski, Jacek ^{[1
]}

机构：

[1] Wroclaw Univ Technol, Dept Organ Chem, Fac Chem, PL-50370 Wroclaw, Poland

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2009年 / 184卷 / 05期

关键词：

Chiral resolution; chiral thioethers; sulfoxidation; ABSOLUTE-CONFIGURATION; ASYMMETRIC OXIDATION; CHIRAL LIGANDS; TRANSFORMATION; SULFOXIDATION; SULFIDES; ROUTE;

D O I：

10.1080/10426500902856420

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A chiral S,S-donating C2-symmetric ligand containing two stereogenic centers was prepared from rac-trans-1,2-cyclohexanediol. An effective deracemization of trans-1,2-bis(phenylsulfenyl)cyclohexane was achieved by the catalyzed enantioselective sulfoxidation, followed by the chromatographic separation of diastereomeric mono- and bis-sulfoxides. Subsequent recrystallization of enantiomerically enriched bissulfoxide and its final deoxygenation gave optically pure (1R,2R)-bis(phenylsulfenyl)cyclohexane.

引用

页码：1323 / 1331

页数：9

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