Escin is a triterpenoid saponin extracted from the fruit of Aesculus wilsonii Rehd. and Aesculus hippocastanum (Hippocastanaceae). Clinically, it is widely used in the treatment of edema induced by either trauma or surgery, as well as treating chronic venous insufficiency. The anti-inflammatory and antiedema effects of escin have been extensively investigated. This article systematically reviews the effects of escin on inflammation and gastrointestinal diseases, including its role in inflammation, as an antioxidant, and in inhibiting gastric acid secretion and promoting gastrointestinal movement, especially, the molecular mechanism. The advantages and potential uses of escin have also been discussed.
机构:
PLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China
PLA 425th Hosp, Dept Neurol, 86 Sanya Bay Rd, Sanya 572000, Peoples R ChinaPLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China
Cheng, Peng
;
Kuang, Fang
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机构:
PLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China
PLA 425th Hosp, Dept Neurol, 86 Sanya Bay Rd, Sanya 572000, Peoples R ChinaPLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China
Kuang, Fang
;
Ju, Gong
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h-index: 0
机构:
PLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China
PLA 425th Hosp, Dept Neurol, 86 Sanya Bay Rd, Sanya 572000, Peoples R ChinaPLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China
机构:
PLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China
PLA 425th Hosp, Dept Neurol, 86 Sanya Bay Rd, Sanya 572000, Peoples R ChinaPLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China
Cheng, Peng
;
Kuang, Fang
论文数: 0引用数: 0
h-index: 0
机构:
PLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China
PLA 425th Hosp, Dept Neurol, 86 Sanya Bay Rd, Sanya 572000, Peoples R ChinaPLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China
Kuang, Fang
;
Ju, Gong
论文数: 0引用数: 0
h-index: 0
机构:
PLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China
PLA 425th Hosp, Dept Neurol, 86 Sanya Bay Rd, Sanya 572000, Peoples R ChinaPLA Fourth Mil Med Univ, Inst Neurosci, 169 West Changle Rd, Xian 710032, Peoples R China