Visible light photocatalytic asymmetric synthesis of pyrrolo[1,2-a]indoles via intermolecular [3+2] cycloaddition

被引：22
|
作者：
Casado-Sanchez, Antonio [1 ]
Domingo-Legarda, Pablo [1 ]
Cabrera, Silvia [2 ,3 ]
Aleman, Jose [1 ,3 ]
机构：
[1] Univ Autonoma Madrid, Organ Chem Dept, Modulo 1, E-28049 Madrid, Spain
[2] Univ Autonoma Madrid, Inorgan Chem Dept, Modulo 1, E-28049 Madrid, Spain
[3] Univ Autonoma Madrid, Inst Adv Res Chem Sci IAdChem, E-28049 Madrid, Spain
来源：
CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 75期
关键词：
RADICAL CYCLIZATION; DIASTEREOSELECTIVE SYNTHESIS; PHOTOREDOX CATALYSIS; CONJUGATE ADDITIONS; ALPHA-SILYLAMINES; BARTON ESTERS; LEWIS-ACID; INDOLE; FUNCTIONALIZATION; CONSTRUCTION;
D O I：
10.1039/c9cc05838a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The intermolecular diastereoselective and enantioselective synthesis of pyrrolo[1,2-a]indoles is developed through a [3+2] cycloaddition between silyl-indole derivatives and alpha,beta-unsaturated N-acyl oxazolidinones by merging photocatalysis and Lewis acid catalysis.
引用
收藏
页码：11303 / 11306
页数：4
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